Ubwino wa ma SAR: Zomwe Muyenera Kudziwa

Ma SAR amapereka zabwino za testosterone popanda zotsatirapo zake. Ma SAR amayimira Selective Androgen Receptor Modulators, ndipo ndi gulu lapadera la mankhwala omwe amapangidwa kuti athetse matenda monga Alzheimer's and osteoporosis. 

Amathandizira pakupanga minofu ndikulimbikitsa kuchepa kwa thupi. Ma SAR ndiotetezeka akagwiritsidwa ntchito movomerezeka, ndipo samathandizira pamavuto am'magazi. Alibe poizoni ndipo samayika chiwindi. Ma SAR atha kuthandizanso pakukonza zovulala zomwe zili ndi miyezi kapena zaka.

 

Zina mwamaubwino a ma SAR ndizowoneka bwino - muyenera kungoyang'ana omanga omwe amalumbira nawo. Komabe, sikuti amangokonzekera mwachangu. 

Kuti mupeze zabwino zonse za ma SAR, muyenera kutsatira njira yoyenera ndikumwa mlingowo moyenera. Ma SAR amagwiritsidwa ntchito ndi omanga thupi, ophunzitsa zolimbitsa thupi, komanso omwe akufuna kutaya mafuta amthupi. 

Pali mitundu yosiyanasiyana ya ma SAR omwe amapezeka ku UK, ndipo amatha kugulidwa pa intaneti kapena m'masitolo apadera. Ma SAR ndiotsika mtengo kuposa ma steroid amtundu ndi ma prohormones. 

 

Kodi Pali Ma SARM Amtundu Wanji?

Imodzi mwa mitundu yatsopano ya ma SAR ndi RAD-140, yomwe yatchuka kwambiri ku UK konse. Ili ndi chidwi cha anabolic ku androgenic ratio ya 90 mpaka 1, kutanthauza kuti anthu omwe amatsata RAD-140 mkombero adzapeza zabwino zowonjezera minofu popanda zovuta zoyipa za mankhwala a androgenic. RAD-140 imachepetsanso zotsatira za testosterone, motero kumachepetsa mavuto a prostate mwa amuna. Kuti mupeze zotsatira zabwino, RAD-140 iyenera kutengedwa mozungulira masabata 4 mpaka 6. 

 

Ostarine ndi SARM ina yodziwika bwino yomwe imagwiritsidwa ntchito ndi anthu ambiri. Amagwiritsidwa ntchito kuteteza minofu ngakhale panthawi yoperewera kwa ma calories. LGD-4033 ndi yofanana ndi Ostarine koma imakhala yamphamvu kwambiri maulendo 12. Zimatsimikiziridwa kuti ndizoyendetsa bwino, mosiyana ndi Ostarine, yomwe imagwiritsidwa ntchito bwino pakucheka.

Ubwino wa SARM iyi ndikuti si-steroid mwachilengedwe ndipo imagwirizana ndi ma androgen receptors mosankha. 

Izi zimapereka chiwongolero chachikulu pamtunduwu kuposa ma steroids: anabolic steroids amamanga pafupifupi selo iliyonse, ndipo nthawi zambiri amatulutsa zosafunika kapena zoopsa. Kunena mwachidule, palibe mphamvu yosankha ngati ma steroids amamanga minofu yanu ndikulimbikitsa kukula, kapena kusokoneza ntchito ya ziwalo zofunika monga mtima wanu ndi chiwindi.

Pambuyo pomanga, LGD-4033 imapanga zotsatira za anabolic mu minofu ndi mafupa, zomwe zimathandiza pakukula ndikulimbitsa matupi amenewa. Kugwiritsa ntchito LGD-4033 kumatanthauza kuti ogwiritsa ntchito amakhala otetezeka ku zovuta zomwe zimadza chifukwa cha mankhwala amtundu wamankhwala - zomwe nthawi zambiri zimatha kubala, ziphuphu, ndi vuto la prostate. 

 

MK-677, kapena Ibutamoren, ndi mtundu wa SARM womwe si peptidic - wopanda peptides - mwachilengedwe. Amatengedwa pakamwa ndikuthandizira kukulitsa minofu ndi kuchuluka kwa mafupa. 

Zowonjezera ngati izi zimalimbikitsa kukula pogwiritsa ntchito Insulin-ngati Growth Factor 1, yotchedwanso IGF-1. Iyi ndi hormone yomwe imatsanzira zina mwazinthu za insulini (koma ndizosiyana ndi mankhwala, choncho siziyenera kugwiritsidwa ntchito m'malo mwake). IGF-1 imapezeka mthupi mwachilengedwe, ndipo imakhala ndi gawo lofunikira pakukula kwaubwana ndi kutha msinkhu. Akuluakulu zachilengedwe zimakhala zazing'ono kwambiri, motero kuwonjezerako kumatha kukhala ndi zotsatira za anabolic. 

 

Ubwino wama SAR pamtulo 

Ma SAR omwe amayambitsa kutulutsidwa kwakukulu kwa IGF-1 mthupi amagwiritsidwa ntchito pakati pa akulu omwe ali ndi kuchepa kapena kuchepa kwamahomoni. Monga ndi chilichonse chomwe chimalimbitsa minofu, zachidziwikire kuti ndiwotchuka pakati pagulu lolimbitsa thupi. 

Kudya tsiku ndi tsiku kwa 25mg ya MK-677 kumatha kukulitsa kuchuluka kwa IGF-1 ndi 60% munthawi yamasabata 6. Izi ndizapamwamba kwambiri kuposa kuchuluka kwachilengedwe komwe zimawonedwa mwa akulu: pambali pa zakudya zopatsa thanzi, zomanga thupi, komanso njira zina zathanzi monga kugona mokwanira komanso kupewa kusuta fodya ndi mowa, ndizotheka kuti ogwiritsa ntchito amange minofu yopitilira momwe angathere pakadali pano wonenepa. 

 

MK-677 siyopanda mahomoni, ndipo zotsatira zabwino zimapezeka ikamazunguliridwa kwa miyezi itatu. Nthawi yabwino kutenga MK-3 ndi usiku, musanagone. Zithandizanso kuti mugone mwachangu, chifukwa chakupezeka kwa mankhwala otchedwa ghrelin. 

Ghrelin mwachilengedwe amapezeka mthupi ndipo ndiye amachititsa kuti thupi lanu lizizungulira, lomwe limafotokozera thupi nthawi yogona komanso nthawi yodzuka. Omwe amavutika kugona bwino amadziwa momwe zimakhudzira moyo watsiku ndi tsiku, makamaka makamaka pakulimbitsa thupi. Apa, maubwino ama SARM atha kukhala owopsa. Sizosangalatsa komanso kutetezeka kunyamula zolemera mukadali mtulo tofa nato!

Ogwiritsa ntchito ambiri amawona kuti MK-677 ili ndi zotsatira zabwino pamachitidwe awo ogona komanso nthawi yogona, komanso malingaliro oti "apumula" ndikuchepetsa kufunika kodzuka usiku. Ngakhale sayenera kutengedwa chifukwa chogona okha, ndi mwayi wodabwitsa wa ma SAR. 

 

Anthu omwe amapindula kwambiri ndi kugwiritsa ntchito ma SAR amawaphatikiza ndi zakudya zopatsa thanzi komanso kuchita masewera olimbitsa thupi pafupipafupi. Dziwani kuti siokonza zamatsenga: kukhala patsogolo pa kompyuta kwa maola ambiri kapena kudya makeke akulu a chokoleti sikungakuthandizeni kuchepa ngakhale mutatenga ma SAR kuti muchepetse kunenepa kwanu! Mukasankha chizolowezi choyenera ndikukhala otetezeka komanso olimbikitsidwa, ma SAR adzakuthandizani kuti mukwaniritse zomwe mukufuna posachedwa. 

 

Ubwino wama SAR pa Khungu

Mwina mudamvapo zowonjezera zowonjezera monga MK-677 (Ibutamoren) wotchedwa "kasupe wachinyamata"! Izi ndichifukwa cha momwe zimakhudzira magulu a collagen mthupi. Collagen imathandizira kulimba kwa khungu ndi tsitsi, ndipo zopangira ma collagen monga mafuta amaso zili ponseponse pamsika kuti zilimbitse khungu lotayirira ndikuchepetsa mawonekedwe azigawo zamdima, makwinya, ndi matumba amaso. Magulu akuluakulu a collagen amapanga khungu lolimba, losalala, komanso laling'ono mukamathandizidwa pafupipafupi. 

Zowonjezera izi sizimangowonjezera kupanga kwa collagen mthupi, komanso zimachepetsa kuchepa kwake. Izi zikutanthauzanso kuti kuvulala kwakale, kwamakani kumatha kupindula ndi kuwonjezeka kwa collagen, ndikutsogolera zilonda ndi minofu panjira yopita kuchipatala. 

 

Ubwino wama SAR pamalingaliro

Ghrelin, mahomoni omwe tidakambirana zakugona, amathandizanso pakugwira ntchito kwamaubongo tsiku ndi tsiku. Ghrelin amapezeka m'ma SARM angapo monga MK-677 (Ibutamoren) ndipo amakhudza kwambiri magawo monga kukumbukira, kulimbikitsa, komanso luso muubongo. 

Mutha kuwona kuti izi zimagwirira ntchito limodzi ndi kugona kwanu komanso kulimbitsa thupi: mukamakhala kupumula kwambiri, mumachita bwino pamoyo wanu watsiku ndi tsiku komanso nthawi yolimbitsa thupi. Mukamachita masewera olimbitsa thupi, mudzagona bwino! Ili ndiye gawo loti "tikhale limodzi" zomwe ndizovuta kuzikonza pomwe othamanga akuthamangitsira mphamvu zochepa. 

"Chifunga cha ubongo" chimakhala choopsa mukakhala ndi mphamvu zolimbitsa thupi, kudzuka m'mawa, kapena kukana zakudya zomwe mumakonda. Zosavuta ngati ma ghrelin zikumveka, ubongo wogwira ntchito umatha kuthana ndi izi ndikukhalitsa okonda kulimbitsa mphotho. 

Ichi ndi china mwamaubwino a ma SAR omwe angawoneke ngati ochepa poyang'ana koyamba, koma ali ndi chimodzi mwazomwe zimapangitsa zotsatira zazitali kwakanthawi kochepa kapena popanda kufunika kochepetsera kapena kupanga nthawi zolemera. Kukhala ndi malingaliro abwinobwino komanso opumula ndikofunikira pakutsatira njira zolimbitsa thupi, ndikukhalabe athanzi kumakupangitsani kuti muzitsatira zolinga zanu. 

 

Kodi Zimagwira Bwanji?

Pali chosowa chachikulu cha ma SAR. Chifukwa chakumanga kwawo minofu ndikuthira mafuta, nthawi zambiri amaikidwa muzowonjezera zomwe zimagulitsidwa kwa okonda kulimbitsa thupi. Endogenous testosterone, yomwe imakhudza kuchuluka kwa mafuta m'thupi komanso kusintha kwa chiwindi (chinthu chodziwika komanso chovulaza chogwiritsa ntchito steroid) chitha kuchepetsedwa kudzera ma SARM. 

M'zaka zaposachedwa, ma SAR akhala akukula padziko lonse lapansi ngati chinthu chovomerezeka; m'maiko ambiri ndizosavuta kugula ndi kugulitsa. Komabe, pansi pa malamulo ambiri, amapezeka kuti mugule pazofufuza zokha.

Izi ndi zomwe zimachitika ku UK ndi USA malamulo, pokhapokha atalamulidwa mwalamulo ndi akatswiri kapena osapatsidwa mankhwala. Zotsatira za ma SAR ambiri chifukwa cha zomwe adalemba monga "mankhwala ofufuzira" kapena "osagwiritsidwa ntchito" ndipo ayenera kutsatiridwa moyenera. Zida zina za SAR zomwe sizimavomerezedwa kuti zigwiritsidwe ntchito zimaphatikizidwanso m'mapapiso ndipo zimagulitsidwa ngati zowonjezera zowonjezera: izi sizogwiritsanso ntchito. 

Izi zati, zimatengera malamulo omwe muli - akatswiri ena azachipatala amatha kupereka ma SAR, ndipo ngati mukukhala kwina komwe ali ovomerezeka kugwiritsa ntchito mankhwala, ingoyenderani malo ogulitsa kapena azachipatala. Apa, mudzatha kupeza ma SARMS odziwika kwambiri ogulitsa omwe akugwirizana ndi zosowa zanu.

Kaya muli ndi mwayi wogwiritsa ntchito malo ngati awa, nthawi zonse ndikofunikira kugwiritsa ntchito magwero odziwika azithandizo zamankhwala ndi minofu. Pano pa Masitolo a SARM, timayesa, kuyesa, ndikupanga zinthu zathu zonse ku UK pansi pa Ma Labbu Omanga. 

 

Steroids vs. ma SAR

Steroids amagwiritsidwa ntchito kupindulitsa minofu, koma mtengo wake ndiwowopsa. Steroids amatumiza gulu la mauthenga osakanikirana ndi mapulogalamu amkati mwa thupi lanu ndikusokoneza ubongo. Izi zikutanthauza kuti zitha kuwononga chiwalo chilichonse: zovuta zitha kukhala mwadzidzidzi komanso zovuta kulosera. 

Steroids ndi ovomerezeka m'maiko ochepa, monga: Canada, Iran, Mexico, Panama, Greece, Poland, Ukraine, India, Pakistan, ndi Japan. 

Ma SAR ndi ma steroids ali ofanana, koma siamodzi. Pali zosiyana zazing'ono koma zofunika pakati pawo:

Ma SAR si chozizwitsa ndipo, ngakhale amapewa zovuta zoyipa za steroids, ochepa amatha kukhalabe. Pali zabwino zambiri za ma SAR; amadziwika kuti ndi otetezeka kuposa ma steroids, koma nthawi zonse ndibwino kukumbukira kuti palibe chilichonse choyera. Ma steroids ndi ma SAR ali ndi zovuta zawo ndipo amayenera kugwiritsidwa ntchito moyenera komanso kufufuzidwa kale asanagwiritse ntchito. 

Ngati mukufunafuna zifukwa zina zakuti ma SAR ndi njira zina zosavulaza, ganizirani kuti ma steroids ndi kuchuluka kwa testosterone mkati mwawo kumatha kuyambitsa tsitsi lowopsa komanso kukula kwa mawere mwa amuna. Zitha kupangitsa ziphuphu zakumaso ndi mavuto amkwiyo, komanso zotsatira zoyipa zazitali ngati chiwindi cha chiwindi. Mosiyana ndi ma steroids, ma SAR amagwira ntchito pakamwa ndipo safuna jakisoni.

Ma SAR si ma anabolic steroids; ndi nthano zopanga zomwe zimagwirizana ndi ma androgen receptors. Kutengera mtundu wamagulu awo, amakhala ngati agonists kapena otsutsana nawo. Pamapeto pake, zatsimikiziridwa kuti maubwino ama SAR ndi zomwe zingachitike pambuyo pake ndizabwino kuposa anabolic steroids. 

 

Kuda nkhawa ndi Kukula Kotchuka Kowonongeka kwa ma SAR

Ma SAR sanalandiridwe ndi a FDA (US Food and Drug Administration) motero amakhala ndi nkhawa zazikulu zachitetezo. Amatha kuwonjezera chiopsezo cha matenda a mtima komanso kuwopseza moyo kapena -kusintha zovuta monga kuwonongeka kwa chiwindi. 

Ngakhale kuti siowopsa kuposa ma steroids chifukwa cha zamankhwala kapena zamankhwala, kuphunzira mwakhama kumakhalabe kwatsopano ndipo zotsatira za nthawi yayitali zamagwiritsidwe ntchito a SARM sizikudziwika. Mpaka mayesero azachipatala ndi kafukufuku akuwonetsa kuti ndi oyenera kugwiritsidwa ntchito popanda kuda nkhawa, simuyenera kuphimbidwa ndi ma SAR.

Ma SAR ndi osaloledwa kumwa kosavomerezeka m'malo ambiri ndipo monga zinthu zonse zosavomerezeka zitha kukhala zowopsa, chifukwa chake samalani ndi zotsatirapo zake ndipo nthawi zonse mupeze malangizo kwa akatswiri ngati mukufuna kuzigwiritsa ntchito.

Mulimonsemo ogwiritsa ntchito sayenera kuwonjezera kuchuluka kwawo chifukwa kumwa mopitirira muyeso kumatha kukhala ndi zotsatira zoyipa kwambiri. Ogwiritsanso akuyeneranso kufunafuna upangiri wa zamankhwala asanatuluke ma SARM kwathunthu ngati njira "yozizira" ingakhalenso yovulaza. 

 

Kodi ma SAR ndiotetezeka kuti angagwiritsidwe ntchito?

Ma ARV amadziwika kuti ndi mankhwala otetezeka kuposa anabolic steroids. Anthu ambiri amafuna kumanga minofu yawo mwachilengedwe popanda zotsatira zoyipa za steroids; munthawi imeneyi ma SAR angakhale yankho. 

Kafukufuku wina akuwonetsa kuti ma SAR amatha kusintha ma cholesterol komanso kuthekera kwawo kukulitsa kuchuluka kwa mafupa. Ngati mukukumana ndi mavuto omanga thupi, atha kukhala yankho. 

Ubwino wina wa ma SAR ndi awa:

• Kutentha mafuta ngati mafuta - kumapangitsa kuti muchepetse thupi komanso "kuwombera":
• Zitha kusintha magwiridwe antchito - kuthamanga kuthamanga ndi mphamvu;
• Kuchepetsa nthawi yothamanga;
• Amathandizira kumanga thupi loonda;
• Ikhoza kukulitsa mphamvu ya mafupa ndi kachulukidwe kake. 

 

Olimba kwambiri mu ma SAR

Ngati mukufunitsitsa kusintha thupi lanu, kulingalira za thandizo la ma ARV mukavomerezedwa kuli ndi mphamvu yosinthira thanzi lanu. Ma SAR amagwira ntchito modabwitsa pomanga mafuta ambiri komanso owotcha mafuta. Monga tafotokozera kale, atha kukuthandizani kuti muchiritse msanga kuvulala: pomwe simuyenera kudzikakamiza musanakonzekere, zitha kukhala zokhumudwitsa kukhala ndikudikirira, ndipo kuvulala komwe kumachitika pambuyo pake kumangochedwetsa izi. Kudzimva wamphamvu mutabwerera m'mbuyo kumabweretsa chidaliro choti mubwerere mofulumira kuposa kale. 

 

Kuti mumve zambiri, omasuka kutero Lumikizanani nafe! Titha kukhala okondwa kwambiri kukambirana nanu mafunso okhudzana ndi kulimbitsa thupi, kapena kupanga ndandanda yomwe ingakhudze moyo wanu komanso zolinga zanu.