Upangiri Wotsogola Kwa a SARM's

WOTSATIRA SARMS

 

Upangiri Wotsogola kwa ma SAR - Ma Modulators Osankha Androgen Receptor

Kulimbitsa minofu yanu ndikofunikira kwambiri ndipo nthawi zonse muyenera kupeza njira yabwino kwambiri, yodalirika yochitira izi osadziika pangozi. Ndipo ndipamene kufunika kosankha ma modulators a androgen amathandizira. Chinthu choyenera kuzindikira za ma SAR ndikuti muyenera kukhala osachepera zaka 18 kuti mugwiritse ntchito izi. Komanso, ndi oletsedwa kumadera ena, osanenapo kuti anthu omwe ali ndi kukulitsa kwa Prostate kapena khansa ya prostate, HDL kapena matenda amtima akuyeneranso kukhala kutali ndi izi. Mukamachita kwambiri izi, zidzakhala zabwino pamapeto pake.

Kodi modulators a androgen receptor modulators ndi ati?

Nthawi zonse mukapita ku Sarmsstore, mukufuna china chake chomwe chimakuthandizani kukulitsa minofu mwachilengedwe. Ndipo ndi zomwe ma modulators a androgen receptor angakuchitireni. Ndi mankhwala omwe amakulolani kuti mulimbikitse zolandila zofunikira mthupi lanu kapena kuziletsa. Zotsatira zake, mudzakulitsa kuchuluka kwa mafupa, minofu ngakhale komanso kuchepa thupi mosavuta.

Izi zilibe chilichonse chokhudzana ndi prostate, komabe zitha kukhala zovuta kwambiri chifukwa ndizovuta kwambiri kuti muzigwiritsa ntchito pafupipafupi. Ndili ndi malingaliro, m'nkhaniyi tikuphunzira zaubwino wosankha ma androgen receptor modulators, zoyipa zawo ndi zina zotero. Mwanjira imeneyi mudzadziwa ngati zopangidwa ngati ma Labu Omangidwanso kapena ena aliwonse ochokera ku Sarmstore zabwino komanso ngati muyenera kuzipeza izi kapena ayi.

Mfundo zofunika kuzikumbukira

Chomwe mungazindikire pamayendedwe amtundu wa androgen ndikuti mukayamba kulankhula za iwo, muyenera kuphunzira mawu oyenera. Ndipo tili pano kuti tikuthandizireni izi.

• Ovariectomized amatanthauza kuti mazira ochotsedwa amachotsedwa
• Orchidectomized amatanthauza kuti machende amachotsedwa, amadziwika kuti ndi nthawi ya amuna okhwimitsa.
• Estradiol ndi mtundu wa estrogen ndipo imatulutsidwa pang'ono mu umuna wamwamuna kuti uwonetsetse kuti umuna sufa mwachangu kwambiri. Kwa amayi, izi zimathandiza kwambiri m'mimba, m'mawere ndi kumaliseche, pakati pa ena ambiri.
• AICAR ndi fanizo la adenosine monophosphate ndipo izi zithandizira kuyambitsa AMPK.
• VLDL amatanthauza lipoproptein yotsika kwambiri, yomwe imadziwikanso kuti cholesterol yoyipa nthawi zambiri.
• LDL ndi cholesterol yabwino kapena lipoprotein.
• AMPK ndi 5 AMP activated kinase. Izi zidapangidwa kuti zithandizire njira ya homeostasis mwachilengedwe. Izi zithandizira kukulitsa makutidwe ndi okosijeni wamafuta acid, triglyceride kaphatikizidwe, kuchuluka kwa shuga wamafuta komanso mafuta okosijeni a asidi.
• PPAR ndi pulogalamu ya peroxisome proliferator yomwe idasinthidwa. Izi ndizofunikira pamalamulo amadzimadzi a lipid ndipo amagwira ntchito bwino kwambiri.
• EB ndi estradiol benzoate ndipo itha kugwiritsidwa ntchito kukhalabe ndi machitidwe ogonana mu makoswe.
• ED50 ndi ma dozes apakatikati omwe angayese kupereka zomwe mukufuna theka la anthu.
• PCT imadziwikanso kuti post cycle therapy ndipo imakhala ndi zinthu zingapo zomwe zimakuthandizani kuyambiranso kupanga testosterone mwachilengedwe komanso bwino.
• BMD ndikulimba kwa mafupa ndipo imawonetsa kuchuluka kwa mchere komwe mungapeze mu sentimita imodzi iliyonse ya mafupa.
• LPL ndi lipoprotein lipase ndipo imasungira mafuta monga mafuta.
• PSA ndimayeso a prostate enieni a antigen omwe amayesa kuchuluka kwa mapuloteni ena omwe amapangidwa ndi prostate gland.
• 5 alpha reductase ndi enzyme yofunika kwambiri yomwe imagwiritsidwa ntchito munthawi ya steroid metabolism.
• Kununkhiritsa kwa mafuta ndi njira yomwe imakupatsani mwayi woti musinthe gawo linalake mu estrogen kapena androgen yogwira ntchito, kutengera momwe zinthu ziliri.
• ALT imayimira alanine aminotransferase ndipo ndi enzyme yomwe imawonetsa kuti mumavulala chiwindi.
• AST ndi aspartate aminotransferase ndi ofanana ndi AST, imawonetsa kuwonongeka kwa chiwindi chilichonse.
• SHBG imayimira mahomoni ogonana omwe amamanga globulin ndipo amamangiriza ku estradiol, DHT ndi testosterone. Mutha kuwona ngati mumatulutsa testosterone wochepa kwambiri kapena wochuluka motere.
• DHT ndi dihydrotestosterone. Iyi ndi steroid yogonana komanso mahomoni a androgen ndipo mutha kuyipeza m'matenda a adrenal, ma follicles atsitsi komanso prostate.
• TP ndi testosterone propionate ndipo ndiwotengera kuchokera ku testosterone yomwe nthawi zambiri imatha kulowetsedwa mu minofu yanu.
• FSH ndi hormone yolimbikitsa. Ndi mahomoni ogwirizana kwambiri ndi kukula kwa umuna mwa abambo ndi kulengedwa kwa dzira mwa akazi.
• LH imayimira mahomoni a luteinizing, hormone iyi imatulutsidwa m'matumbo a pituitary ndipo ngati ndi yochulukirapo kapena yocheperako mudzakhala ndi vuto la kusabereka kapena zovuta zina.
• Mzere wa HPG ndiye hypothalamic pituitary gonadal axis. Mawuwa amafotokoza ma gland atatu omwe amapezeka mu endocrine system, koma onse ndi gawo limodzi.

Kodi modulators osankhidwa ndi androgen receptor adayamba bwanji kupangidwa?

Ofufuzawa adayamba kusintha kapangidwe ka ma molekyulu a testosterone m'ma 40s ndipo izi zoyambira zimawoneka ngati steroidal. Kampani yoyamba yomwe idayamba kupanga ma quinolinones ozungulira anali Ligand Pharmaceuticals ndipo awa anali mankhwala oyamba omwe amadziwika kuti nonsteroidal selective androgen receptor modulators.

Kwa zaka XNUMX zapitazi ofufuza adakwanitsa kusintha zambiri zikafika pakupezeka kwa mankhwalawa. Ayeneranso kuchepa kuchuluka kwa kawopsedwe komwe kali nako, chomwe ndichinthu chabwino kwambiri.

Mosiyana ndi mankhwala ena ofanana, ma SAR amachita molunjika pazolandila zina za androgen. Izi zimapezeka m'magawo osiyanasiyana mthupi lanu, kaya ndi khungu lam'mimba, Prostate, chichereŵechereŵe, mafinya a thukuta, maubweya a tsitsi, minofu yosalala, adrenal cortex, ubongo ndi chiwindi, pakati pa ena ambiri.

Chimodzi mwazifukwa zomwe ma modulators osankhidwa ndi androgen amathandizira ndikuti amuna ambiri samatulutsa testosterone yokwanira. Zitha kukhala zokhudzana ndi msinkhu, kuvulala ndi zina zotero. Hypogonadism monga chonchi imatha kukhala vuto chifukwa pamapeto pake mumakhala ndi libido yotsika, kukhumudwa, mumadzikundikira mafuta ochulukirapo ndipo libido imakhalanso yotsika.

Kugwiritsa ntchito Selective Androgen Receptor Modulators ndikwabwino ngati mukufuna kupititsa patsogolo kufalikira kwa DHT ndi androgen receptor ligands testosterone. Powonjezera magawo achilengedwe, mumatha kuthana ndi hypogonadism, ndipo mutha kumaliza kuthana ndi zovuta zilizonse zokhudzana ndi msinkhu wanu, osatchulanso zovuta zowononga minofu. Ndipo zonsezi ndizotheka popanda vuto lililonse ku prostate, komwe ndikofunikira kwambiri kukumbukira.

Nthawi zambiri ma Selective Androgen Receptor Modulators amakhala ndi zochita za wotsutsana nawo mu prostate ndipo amakhala agonist m'mafupa ndi minofu. Chifukwa chake zimatha kukhudza mafupa ndi minofu popanda kukhudza prostate kwambiri. Izi ndi zinthu zofunika kuzikumbukira mukamaganizira zinthu zamtunduwu.

Mudzawona pali njira ziwiri zazikulu zopangira Selective Androgen Receptor Modulators. Yoyamba imatchedwa njira yotsika kwambiri ndipo ofufuza amasankha zochitika zina ndi mbiri yakusankha kwaminyewa. Izi zitatha, apanga SARM yomwe mukufuna malinga ndi mbiri yomwe mukufuna.

Kumbali inayi, pali njira zam'munsi zomwe zimafunikira kuti mudziwe njira ya androgen paminyewa yamafupa ndi prostate. Zimatengera momwe ochita kafukufuku angathandizire kupanga SARM moyenera. Kwenikweni iliyonse mwanjira ziwiri izi ndiyabwino kwambiri, ndipo imadza ndi maubwino ake. Koma kutengera zofunikira zonse, pangakhale lingaliro labwino kusankha limodzi. Zomwe zimakhalabe zabwino nthawi zambiri kuposa ayi.

Popeza ma Selective Androgen Receptor Modulators ndiabwino kwambiri, bwanji osapatsidwa kwa odwala nthawi zambiri? Izi zimagwiritsidwa ntchito pamayesero azachipatala, koma palibe imodzi mwazomwe zakhala zotsogola kwambiri makamaka pagawo la 4 kapena mayesero amtsogolo. Ndiye chifukwa chake sitikuwona zotsatira zonse za izi.

Palinso zowona kuti maphunziro ambiri opangira Selective Androgen Receptor Modulators adachitidwa pa makoswe. Zina mwazo zimapangidwa ndi makoswe osenda, ena makoswe osakanizidwa. Ochita kafukufuku amayesa zinthu monga kukula kwa minofu, gawo la estrogen ndi zina zambiri.

Chomwe muyenera kukumbukira pakadali pano ndikuti makampani ambiri a sayansi yamoyo ndi ma pharma padziko lonse lapansi akupanga ndikupanga ma Selective Androgen Receptor Modulators. Komabe, izi sizomwe aliyense angagwiritse ntchito. Monga tanena kale zoletsedwazo zilipobe, komabe pali makampani ambiri omwe amagwira ntchito ma SARM nthawi zonse. Izi zikuphatikiza Bristol Myers Squibb, GTX Inc, GlaxoSmithKline, Johnson ndi Johnson, Kaken Pharmaceuticals, Ligand Pharmaceuticals, Merck ndi ena ambiri.

Makampani onse omwe atchulidwawa akupanga ma SAR ndi cholinga chothandiza anthu ambiri. Zogulitsa zawo ndizabwino kwa azimayi omwe atha msambo komanso achikulire omwe sanathenso. Awa ndi magulu awiri akulu omwe amakhudzana ndi mavuto akulu monga kupindula kwamafuta, kusayenda pang'ono, mphamvu ndi kuchepa kwa minofu. Ayeneranso kuthana ndi mafupa osalekeza, zomwe ndizofanana ndi zomwe Selective Androgen Receptor Modulators zitha kuthandizira ndikukweza. Ndi chinthu chomwe chimagwira ntchito ndipo mudzakhala osangalala ndi zotsatira zake.

China chofunika kudziwa ndichakuti IOC idawonjezera Selective Androgen Receptor Modulators pamndandanda wazinthu zoletsedwa. Amaletsedwanso pankhani yamabungwe ambiri azamasewera monga WADA ndi NCAA, osatchulanso mabungwe olimba, olimbitsa thupi ndi olimbikitsa magetsi. Izi sizimawapangitsa kukhala oyipa kapena chilichonse, zimangowonetsa kuti ali kunja kwa zinthu zomwe zimaloledwa. Chifukwa chake ngati mukufuna kukhala nawo pamasewera kapena zochitika ngati izi, muyenera kuwapewa. Kupanda kutero, ngati madotolo ati zili bwino kuzigwiritsa ntchito muyenera kuwombera chifukwa ndiabwino ndipo ndi ena mwa mayankho abwino kunja uko.

Chifukwa chiyani muyenera kugwiritsa ntchito Selective Androgen Receptor Modulators?

Makampani ambiri monga ma Labu Omangidwa Ndi Thupi amalimbikitsa anthu kuti athetse mantha omwe angakhale nawo ndikugwiritsa ntchito ma SAR. Ndipo ndikosavuta kuwona chifukwa. Zinthu izi zikukupatsani maubwino odabwitsa. Izi zikuphatikiza kuchepa kwamafuta, kuchuluka kwa mafupa ndi minofu komanso zina zazikulu. Izi zonse zimaphatikiza kuti zibweretse patsogolo zotsatira zabwino.

Ngakhale anthu ambiri atanena kuti izi ndi za othamanga, sizomwe zili choncho. M'malo mwake anthu ambiri atha kupindula nawo. NGATI muli ndi mavuto owononga minofu, kufooka kwathunthu, kuwonongeka kwa thupi chifukwa cha HIV ya Cancer kapena kuwotcha, kuvulala pamasewera ndi zina zotero, mutha kugwiritsa ntchito Selective Androgen Receptor Modulators popanda zovuta zambiri.

Komabe muyeneranso kukumbukira kuti pali mankhwala ambiri omwe amakhala abwino kwambiri kuti mukhale athanzi komanso okhazikika. Komabe, Selective Androgen Receptor Modulators sakhala onunkhira komanso osakhala methylated ndi thupi. Zinthu zambiri zimatha kubweretsa zovuta za chiwindi ndipo nthawi zina ngakhale kulephera. Ma SAR samachita izi. Ndiabwino ngakhale mutadwala kwambiri, ndipo amapanga chilichonse kuti athe kukuthandizani kuti mukhale ndi moyo wabwino m'njira zomwe simungamvetse. Inde, ngati mukufuna kukhala ndi moyo wabwino pakapita nthawi, kugwiritsa ntchito Selective Androgen Receptor Modulators kungathandizenso. Koma ndibwino kuyankhula ndi madotolo kuti mukhale otetezeka.

Maphunziro ambiri a SARM adachitika pa makoswe ndipo izi zikuwonetsa kuti kulemera kwa Prostate sikukhudzidwa ndikukula kwa minofu. Ndipo ndizabwino, chifukwa kuchepa kwa kulemera kwa prostate kumatha kukhala kovuta kwambiri ndipo kumatha kubweretsanso zovuta zake. Kutengera mayesero a SARM opangidwa ndi anthu, maphunziro ena adakhala onenepa ndi 1-1.5 kg mpaka mwezi umodzi ndi theka. Komabe, ichi chinali chiyeso kwa anthu wamba, kafukufuku wa iwo omwe amachita zolimbitsa thupi nthawi zambiri amakhala ndi zotsatira zosiyana, chifukwa chake yesani kuziwona.

Phindu lina lalikulu la ma SAR ndikuti ali ndi luso lochepetsa kapena kusiyanitsa zinthu ngati kupindika kwa minofu. Ngati mumagwira ntchito molimbika kuti mupange minofu yolimba komanso nyonga, mukufunikiradi njira yowonjezera zotsatira ndikufulumizitsanso kuchira. Izi zimakuthandizani kuchita izi. Imakupatsani kuyendetsa, kuyang'ana komanso kuthamanga. Ndipo ndiye mtundu wa chinthu chomwe mukuyembekezera munyengo ngati iyi.

Mupezanso Selective Androgen Receptor Modulators omwe amathandizira ma AMPK, omwe ndi njira zomwe zimathandizira lypolisis ndi mafuta okosijeni. Mankhwala omwe amachokera ku testosterone amachepetsa kuchuluka kwa mafuta ndikulimbikitsa minofu. Komabe sali otetezeka monga Selective Androgen Receptor Modulators, omwe nthawi ndi nthawi adakwanitsa kuteteza thupi ndikubweretsa zinthu zomwe zitha kuwononga monga zimakhalira kuchitika nthawi zina.

Choyenera kuganizira ndikuti ma androgens amatha kukulitsa mafupa a periosteal ndipo mankhwala a estrogen amachepetsa mapangidwe awa. Chifukwa chake inde, ma androgens akumangadi gawo lakunja la fupa ndipo zimathandizira posungira calcium, chitetezo chamthupi ndi zina zambiri.

Modulators a Androgen Receptor Modulators ali bwino pochepetsa ma trabecular komanso endocortical bone. Izi ndizofunikira chifukwa amalumikizana mosavutikira ndi kutayika pang'ono kwa mafupa, osanenapo kuti mafupa anu azitha kusinthasintha ndipo mafupa azigwira ntchito bwino kuposa kale. Zinthu zonsezi ndizofunikira ndipo muyenera kuzikumbukira!

Chifukwa cha kuchepa kwa mafupa komanso kuwonjezeka kwa mafupa ndikosavuta kuwona kuti Selective Androgen Receptor Modulators imathandizira kwambiri mukamalimbana ndi kufooka kwa mafupa. Vutoli limawonekera pomwe kukhazikitsidwa kwa mafupa atsopano sikungayende limodzi ndi kuwonongeka kwa mafupa akale. Nthawi zambiri azimayi omwe amasamba kusamba amakonda kuthana ndi zinthu zamtunduwu, komabe ma SAR ndi omwe amakubweretserani zabwino zambiri, monga kusungitsa mafupa athanzi komanso kuwonongeka kwakukulu.

Mudzawona kuti makampani olimbitsa thupi akugwiritsanso ntchito ma SAR pazinthu monga kupititsa patsogolo kutayika kwa mafuta, kusunga misa yowonda, kukulitsa minofu komanso kukulitsa mphamvu ya minofu ndikupangitsa kuti njira yovutikira ikhale yosavuta. Ochita masewera amatha kugwiritsa ntchito Selective Androgen Receptor Modulators pakati pama testosterone, ma AASs ndi ma pro-mahormone. Zomwe zikutanthauza kuti awa akuyenera kuyang'aniridwa kuti agwire momwe iwo akufunira.

Mosiyana ndi njira zina zonse zomwe zili pamwambapa, Selective Androgen Receptor Modulators zikukuthandizani kupewa zovuta monga khansa ya prostate, kukula kwa tsitsi la thupi, kukula kwa mawere achimuna, mavuto a chiwindi, kuthamanga kwa magazi, dazi, ziphuphu ndi zina zambiri. Zomwe mukufuna kuchita ndikupewa mavuto onsewa, chifukwa chake kugwiritsa ntchito SARMS ndiye njira yoyenera.

Zachidziwikire, mutha kuyendera Sarmstore ndikugula Ma Selective Androgen Receptor Modulators, komabe ndibwino kuti muyankhulane ndi akatswiri musanachitike. Ndizabwino kwambiri, koma kuwonetsetsa kuti mumagula ndalama zokwanira ndizofunikira pano. Thandizo la akatswiri likuthandizani kuti mupindule kwambiri ndi ma SAR, ndichifukwa chake muyenera kupewa kuwatenga nokha!

Ma SARs Otchuka

Apa tikambirana ma SARM otchuka kwambiri, kuchuluka kwake ndi zotsatira zake. Mwanjira imeneyi mudzakhala ndikumvetsetsa bwino zomwe ma SARM amachita komanso momwe mungawagwirire kapena momwe amagwirira ntchito poyambira.

Andarine

Chofunika kukumbukira ndi chakuti Andarine imagwira pakamwa ndipo imasankhanso minofu. Izi zimathandizira kulimbikitsa ziwalo za anabolic, nthawi zina kuposa kuposa za androgenic. Sichikulitsa milingo iliyonse ya estradiol, kapena kupondereza milingo ya FSH kapena LH, yomwe ndiyofunika kwambiri. Zomwe zimachita ndikuti zimakupatsani mwayi wolimbitsa mafupa ndi minofu popanda kuda nkhawa ndi zovuta zilizonse za prostate. Matenda a prostate ndi chiopsezo chachikulu, ndichifukwa chake Andarine ndi wabwino kwambiri. Zachidziwikire, chimamangiriza 33% kuzomvera za androgen, koma sizimabwera ndimavuto aliwonse azaumoyo, m'malo mwake zimangoyang'ana kugwiritsidwa ntchito kwa mafupa ndi minofu.

Pali njira zambiri zogwiritsira ntchito Andarine, nthawi zambiri mudzawona kuti imagwiritsidwa ntchito panthawi yamafuta. Imakwanitsa kuchepa LPL ndipo nthawi zina ogwiritsa ntchito amafotokoza zomwe zikuwonjezera kuchepa kwamadzi. Chifukwa chake ngati mukufuna kuwonjezera minofu yanu pang'ono ndikumachotsanso mafuta, iyi ndiyo njira yabwino kwambiri yochitira. Koma pali zovuta zina mukamachepetsa kuchuluka kwake kuposa 50 mg patsiku. Zosokoneza masomphenya ndizovuta, ndiyeno palinso kuponderezedwa kwa mzere wa HPG womwe ndikofunikira kuthana nawo. Muyenera kuyandikira SARM iliyonse mosamala ndikulankhula ndi dokotala zisanachitike. Zowona, ndizabwino, koma amakhalanso ndi zotsatirapo ndipo ndizolimba kwambiri, chifukwa chake simudziwa zomwe zimakhudza thupi lanu.

Ngati mukufuna kuigwiritsa ntchito kuti mupeze mphamvu, 50 mg patsiku mpaka masabata a 6-8 azikhala ofunikira. Kubwezeretsanso kumafunikira kuti mupite ku 75 mg nthawi zina kwa masabata 4-8. Ponena zodula, 50 mg patsiku kwa masabata 6-8 sizikhala bwino. Kafukufuku wamakoswe akuwonetsa kuti Andarine amatha kulimbitsa mphamvu ya mafupa, ichepetsa mafuta ndikuthandizira kukonza magwiridwe antchito a mafupa. Ichepetsanso kuchepa kwamavuto. Chifukwa chake ngakhale itakhala ndi gawo locheperako, imapindulitsanso.

Ostarine

Pamene Ostarine idagwiritsidwa ntchito pa amuna ndi akazi achikulire 120 athanzi, idawonetsa kuti imatha kukulitsa thupi lowonda. Zimathandizanso kukhudzidwa ndi insulini, osatchulanso kuti zimatha kulimbitsa magwiridwe antchito ake. Kugwiritsa ntchito kulimbitsa thupi kudzakhala kwabwino ngati mungawombere panthawi yobwezeretsa komanso kugwedeza. Sipangakhale kuwonjezeka kwakukulu kuchokera pa bat, koma zotsatira zake zonse zimakhala zodabwitsa kwambiri.

OStarine imathandizira kubwezera ngati mutenga mozungulira 25 mg patsiku, ndipo izi zitha kugwira ntchito momwe mungafunire. Kuti mubwezeretsenso muyenera kutenga chimodzimodzi, zonsezi zidzafunika chithandizo chamasabata 6-8. Ikhoza kuthandizanso kudula, komanso kukonzanso kuvulala. Kwa womalizirayu mukufuna 12.5 mg patsiku, pomwe pocheka mutha kupita 15-20 mg patsiku chifukwa zimayenda bwino pamapeto pake, chifukwa chake yesani kuganizira zonsezi kuti mupeze zotsatira ndi mtengo womwe mukuyembekezera kumapeto,

Ligandrol

Ma SAR nthawi zonse amakhala amphamvu kwambiri ndipo iyi idagwiritsidwa ntchito poyesa mayeso azachipatala a gawo 1, ndiye chinthu choyenera chomwe chimagwira ntchito bwino. Chomwe mungazindikire ndikuti imalimbikitsa thupi lowonda, imatsitsa mafuta ndipo imalimbitsa mphamvu. Zikuwonekeranso kuti zimathandizira kukulitsa lingaliro la kukhala ndi moyo wathanzi, zomwe zingakhale zofunikira kwambiri kuti muwone ndikuganizira, chifukwa chake yesani kuziganizira.

China chomwe muyenera kukumbukira ndikuti Ligandrol amathandizira kuchepetsa kuchuluka kwa mafupa. Izi, kuphatikiza pazofufuza zina zonse zikusonyeza kuti mutha kugwiritsa ntchito SARM iyi ngati chilichonse monga kupezera mphamvu, kubwezeredwa, kudula komanso kuwombera. Izi zikunenedwa, kuchuluka kwa masabata asanu ndi atatu azachipatala kumasiyana. 8-5 mg patsiku la kugwedeza, 10-5 mg wobwezeretsanso ndi 8-3 mg wa kudula. Mutha kuyikanso ndi Ostarine, Cardarine ndi Andarine podula ngati mungathe, zomwe zingakuthandizeni.

Komabe, musayembekezere kuti ichepetsa FSH kapena LH. Imachepetsa testosterone yaulere kapena yathunthu, chifukwa chake yesani kuganizira zonsezi. Ndikofunika kumvetsetsa kuti chophatikizachi chimakhala ndi malire, koma chimagwira bwino ntchito mukachigwiritsa ntchito mokwanira.

BMS-564,929

Iyi ndi SARM yopanda ma steroidal yomwe imagwira pakamwa. Zapangidwa kuti zithetse kuchepa kulikonse kwa ntchito zokhudzana ndi msinkhu. Amanenedwa kuti ndiopambana kwambiri poyerekeza ndi testosterone pakulimbikitsa kukula kwa minofu. Nthawi zambiri itha kukhala imodzi mwanjira zabwino kwambiri za Anabolic SARM pamsika ndipo ndizosavuta kuzipeza ndikuzigwiritsa ntchito.

AC-262,356

Wopangidwa ndi Acadia Pharmaceuticals, mankhwalawa amapereka mphamvu ya stellar anabolic yomwe ili pafupifupi 66% yamphamvu ngati testosterone. Popeza sizimakhudza seminal vesicle ndi kulemera kwa prostate, zimathandizadi kwambiri ndipo zimapereka zotsatira zabwino ndi maubwino. Zitha kukhala zabwino kwambiri kukuthandizani kukulitsa minofu, osanenapo kuti imathandizanso pakukhazikitsa mahomoni, zomwe ndizofunikira kwambiri kuziganizira.

JNJ-28330835

Iyi ndi SARM yina yomwe imagwira pakamwa yomwe ingathandize kuchepetsa kulemera kwa prostate ndikuthandizira kukula kwa minofu. Mukufuna kumwa pafupifupi 10 mg / kg kuti mukhale otetezeka. Amati mankhwalawa amatha kukhudza prostate yamunthu, komabe kuwonongeka konse sikudziwika ndipo ndikofunikira kukumbukira kumapeto. Zimathandizira kuthana ndi mafuta nthawi zambiri, komanso zimawonjezera chilakolako chogonana cha makoswe achikazi, nthawi yonseyi ikamachepetsa chiwongola dzanja, chifukwa chake yesetsani kukumbukira izi. Zitha kubweretsa zovuta zina, chifukwa chake zovuta zomwe mungathane nazo ndizovuta kwambiri.

LGD 2226

Mukamagwiritsa ntchito SARM iyi mutha kukulitsa magwiridwe antchito popanda kuwononga kukula kwa prostate, chonsecho mukukulitsa mphamvu ya mafupa ndikulimbikitsa minofu. Pa chithandizo chomwe chinatenga pafupifupi miyezi 4, zinali zowonekeratu kuti SARM iyi imathandizira pakupanga mafupa komanso imalepheretsa kuchuluka kwa mafupa. Zimathandizanso kukulitsa minofu. Ndipo inde, zimathandizanso pakukweza zogonana zomwe ndizosangalatsa. Koma kafukufuku wina amafunika pamutuwu.

LGD 3303

LGD 3303 idathandizira kwambiri pakukulitsa minofu ndi BMD mumitundu yamakoswe. Sizimasokoneza kukula kwa prostate, chifukwa chake sizovuta pamavuto a androgenic. Izi zikunenedwa, mutha kusankha kulowetsedwa kosalekeza kapena kugwiritsa ntchito pakamwa ngati mukufuna. Ngakhale mutakhala ndi chigawo chachikulu m'thupi lanu, minofu imakulitsa kukula kwake. Ndi chinthu chosazolowereka pazogulitsa zilizonse za SARM, koma zikuwonetsa kuti ndizotetezeka kwambiri poyerekeza ndi zina zomwe mungapeze kumeneko. Tcheru ndi chidwi chenicheni ndizofunikira apa, ndipo zotsatira zake zitha kukhala zabwino kwambiri pamapeto pake.

S-40503

Mudzawona S-40503 ngati SARM yayikulu yokonzedwa kuti ikulitse minofu ndikuwonjezera BMD. Zitero chimodzimodzi ndi DHT koma osadandaula za zovuta zilizonse. Malingana ndi ochita kafukufuku, mankhwalawa ndi otetezeka ndipo amachititsa kuti akhale SARM yabwino kwambiri ya anabolic. Makoswe omwe adalandira izi adakhala ndi kuchuluka kwa 150% kwa kulemera kwa prostate ndipo zomwe zidadzetsa mavuto pokodza. Komabe, mphamvu ya biomechanical ya cortical bone idathandizidwanso.

Ndizosangalatsa kuwona kuti mutha kuwonjezera izi ndikuzigwiritsa ntchito kwa akazi ndi abambo. Koma angagwiritse ntchito chiyani? Ngati mukufuna kuwonjezera minofu yanu, kuchuluka kwa mafupa ndi mphamvu, ichi ndiye njira imodzi yabwino kwambiri yomwe mungaganizire.

S-23

S-23 imadziwika kuti imakhala yolumikizana kwambiri kwambiri ndi ma androgen receptors. Kutengera kafukufuku waposachedwa wokhudzana ndi izi, akuti zithandizira kuchepetsa kukula kwa prostate, kukuthandizani kuti muchepetse kuchuluka kwa mafuta ndikulimbikitsanso minofu. Itha kugwiritsidwanso ntchito ngati njira yolelera yosinthira makoswe ngakhale yaying'ono. Mlingo woyenera ukhoza kukhala 63.5 mg komanso mozungulira 11.75 mg patsiku, ndizomwe mukusowa panthawiyi.

Pali zabwino ndi zoyipa kuzigwiritsa ntchito, monga momwe mungaganizire. Pa dzanja loyamba mwachulukitsa kukula kwa minofu yomwe ili yabwino kwambiri, komabe kuchepa kwa milingo ya LH ndi mavuto amakulidwe a prostate ndi vuto. Komabe, idakulitsa BMD ndikuchepetsa mafuta m'makoswe. Nthawi zambiri kuchuluka kwa pafupifupi 14.9 mg patsiku kumakhala kopambana. Chithandizo chitatha, kusabereka kunasinthidwa ndipo maanja amphaka amayembekezera kutenga pakati, zomwe ndizosangalatsa kupeza. Zachidziwikire kuti kuyesedwa kwachipatala kwa anthu kumafunikira, koma zotsatira zake ndizokhulupirira pang'ono.

Cardarine

Amadziwikanso kuti gulu la GW-501516, ichi ndi chosankhira chomwe chimasankha ndipo chimamangiriza kwa olandila a PPAR. Mukakhala m'dongosolo lanu zidzakuthandizani kuti muzisakaniza mafuta acids. Ikuthandizaninso kukulitsa kutengeka kwa shuga wamagulu, komwe ndikofunikira kwambiri kukumbukira ndikulingalira. Pawuniyi imatha kuthana ndi zovuta zambiri zisanachitike matenda ashuga. Poganizira kuchuluka kwa anthu padziko lonse lapansi omwe ali pafupi kuthana ndi matenda ashuga, izi ndizosangalatsa komanso yankho labwino.

Kupatula apo, kuyesa kwamakoswe ndi mayeso a nyani kunawonetsa kuti imatha kupanga minofu ndikuwotcha mafuta, osanenapo kuti imachepetsa mawonekedwe a matenda a shuga obwera chifukwa cha zakudya. Komabe, choyipa chake ndikuti imatha kuyambitsa khansa pamapeto pake. Komabe, izi ndizokhudzana ndi kugwiritsa ntchito miyezo yayitali m'kupita kwanthawi, ndipo ndichinthu chofunikira kukumbukira. Ngakhale Cardine sakuwoneka ngati SARM yathunthu, WADA ndi IOC adaganiza zoletsa njira iliyonse, makamaka chifukwa imayambitsa AMPK ndipo ndiyomwe imagwiritsa ntchito modabwitsa.

Koma kafukufuku wowerengeka akuwonetsa kuti Cardine alibe vuto lililonse, ndiye kuti siowopsa, komanso samapondereza mahomoni. Ndibwino kuigwiritsa ntchito mozungulira 10 mg patsiku kwa masabata asanu ndi atatu ndipo izi zithandiza kwambiri. Kupirira kwanu kwa anaerobic kudzawonjezeka, chimodzimodzi ndi kupirira kochita masewera olimbitsa thupi. Ndipo zikuwonekeranso kuti muli ndi vuto loyambiranso mwachangu komanso bwino, chomwe ndichinthu chofunikira kwambiri kuganizira ndikumbukira kuyambira pomwepo. Mutha kuyamba ndi mulingo womwewo ndikulankhula ndi adotolo, ndiye ngati mukufuna kuwonjezera zina muzitha kutero pang'onopang'ono. Zimagwira ntchito ndipo mutha kuzisintha mogwirizana ndi zomwe mukufuna.

Zida zofanana ndi ma SAR

Ma SAR ndiabwino koma mudzawonanso kuti pali mitundu ina yazinthu zomwe zitha kugwiranso ntchito bwino pamtundu uwu. Komabe, simudziwa ngati pali zovuta zina m'malo mwawo kapena ayi. Nthawi zambiri sipakhala zovuta zina chifukwa amayesa kutsanzira maubwino osabweretsa zoopsa zilizonse.

Ntchito Nutriceuticals mwachitsanzo ikupereka RPM. Ili ndi chomera chochokera ku P- SARM Synthase AI zovuta mozungulira 344 mg pa kapisozi iliyonse. Chogulitsidwacho chimabwera ndi zowonjezera monga zipatso za machungwa macfaydven, chotsitsa cha mphesa, l-arginine base ndi epimedium grandiflorum kuyamba, ndipo ndichofunikira kwambiri kuganizira. Mlingowo umasiyana kutengera kulemera kwanu, koma muyenera kutenga ola limodzi musanachite masewera olimbitsa thupi. Ngati muli ndi ma lbs 1 mutha kutenga kapisozi ndipo ma 140 lbs onse mutha kuwonjezera kapisozi imodzi, mpaka mutakhala pafupifupi 20+ lbs, mukatero mutha kumamatira ku makapisozi a 220. Mitengo ndiyabwino ndipo mumalandira makapisozi okwana 5.

LG Sciences imakupatsirani 6-Mass, izi zimakupatsani hormone ya anabolic mu 25 mg komanso kuphatikiza kwa kampani. Kuphatikiza kwawo kuli ndi 328 mg, imaphatikizapo piperine 90%, chotsitsa cha manyumwa, mbola ya nettle, chotsitsa cha ginger, D-Aspartic Acid ndi mitundu ina yayikulu. Mukulimbikitsidwa kuti mugwiritse ntchito mapiritsi atatu patsiku ndipo mutha kugawa muyezo wa mphindi 3 musanadye. Chitumikireni ndi ma ola 30 amadzi kuti mupeze zotsatira zabwino. Mukufuna kuwonetsetsa kuti mumagwiritsa ntchito izi mpaka masabata 12, choncho yesani kuganizira zonsezi ngati mukufuna kupeza zotsatira zabwino.

Sayansi ya LG imanena kuti ngati ndinu wogwiritsa ntchito kwambiri mutha kupita ndi mapiritsi a 6 patsiku ndipo zozungulira zitha kukhala masiku 120 chonse. Simudzakhala ndi zovuta ngati mutayang'anira mlingowo. Ngati mungapite ndi masiku 120 ngati nthawi yothandizira, mufunika kupumula kwamasabata anayi. Mumalandira makapisozi 4 pa kugula, ndiye mumalandira ma servings 90-15 pa botolo kutengera momwe mumafunira kuwagwiritsa ntchito kangati.

Kuyesa ma SAR

Izi ndizotheka, koma muyenera kuzindikira kuti ma SAR ali ndi magawo awoawo pamavuto. Zotsatira zakanthawi yayitali za ma SAR sizodziwika bwino, chifukwa chake muyenera kuphunzira izi momwe mungathere kuti mupewe zovuta zilizonse. Ndi lingaliro labwino kwambiri kudziwa zomwe mukulowa, ndipo zotsatira zake zitha kuwala chifukwa cha izo. Palinso ma SAR omwe adayesedwa kuchipatala ndipo ena samayesedwa. Ndikofunikira kuti muwone zomwe SARM mukufuna kugula ndikuwona ngati zikuvomerezedwa ndi FDA kapena ayi. Mwanjira imeneyi mutha kuwonetsetsa kuti palibe zovuta zazikulu ndipo pamapeto pake zitha kukhala mwayi wanu, mutha kukhala otsimikiza.

Ngakhale zili choncho, kuganizira nokha mukamasankha ndi kugwiritsa ntchito ma SAR ndikofunikira. Ili ndi kuthekera kochita bwino kwambiri, ndipo pali zosankha zingapo zomwe mungaganizire zikafika pazinthu ngati izi.

Nthawi zambiri ma SAR amakhala abwino kwambiri zikafika pakulimbikitsa minofu, kutsitsa kuchuluka kwamafuta mthupi lanu komanso kulimbitsa mphamvu ya mafupa anu. Komabe, zitha kukhalanso zovuta chifukwa simudziwa zotsatira zenizeni za thupi lanu mpaka mutayesera. Kugwira ntchito limodzi ndi akatswiri azachipatala ndichinthu chofunikira kwambiri chifukwa simudziwa zomwe mukupanga ndi zinthu ngati izi pokhapokha mutayesetsa. Izi sizitanthauza kuti chikhala chinthu chosavuta kuchita, koma ROI itha kukhala yayikulu kwambiri, chifukwa chake yesani kulingalira zosankha zonse zomwe zingatheke.

Chinthu chimodzi ndi chotsimikizika, ndikuwongolera koyenera mupeza kuti ma SAR amapereka thandizo ndi kufunika komwe mukufuna. Zimagwira bwino kwambiri ndipo mutha kuzisintha kuti zigwirizane ndi zosowa zanu posachedwa. Ngakhale ma SAR ena ali ovuta kusintha moyo wanu watsiku ndi tsiku, zotsatira zake zitha kukhala zachiwiri kwa palibe.