Monga momwe dzina lake likusonyezera, Ibutamoren ndi mankhwala osakhala a peptide omwe amalimbikitsa kukula kwa hormone polimbikitsa chithokomiro cha pituitary.
Ibutamoren sagwira ntchito ngati anabolic steroids, zomwe zimakhudza thupi la androgen receptors. M'malo mwake, imayang'ana ma receptor osiyanasiyana omwe amayang'anira katulutsidwe ka mahomoni okula komanso njira za metabolic.
Popeza MK-677 sichimakhudza katulutsidwe ka testosterone, thupi lanu silimakhudzidwa ndi kusokonezeka kwa mahomoni ndi zotsatira zina zosasangalatsa, monga ndi mahomoni a steroid. Choncho, palibe chifukwa cha chithandizo cha post-cycle.
Kodi Ibutamoren / Nutrobal (Mk-677) Ndi Chiyani Kwenikweni?
Ibutamoren, yemwenso amadziwika kuti Nutrobal ndi MK-677, ndi agonist wosankha wa ghrelin receptor ndi kukula kwa hormone secretagogue. Zotsatira zake, zimachulukitsa insulini-monga kukula kwa 1 (IGF-1) ndi kutulutsa kwa hormone yakukula.
Nutrobal poyambilira idapangidwa kuti ithandizire kudwala matenda osteoporosis, kuwonongeka kwa minofu, ndi kunenepa kwambiri. Hormone iyi yomwe imayendetsedwa pakamwa ndi secretagogue imasonyezedwanso pochiza odwala okalamba omwe amathyoka m'chiuno.
Njira Yoyeserera Ya Ibutamoren
Nutrobal imagwira ntchito popititsa patsogolo kutulutsidwa kwa GHRH (hormone ya kukula-kutulutsa timadzi). Monga momwe dzina lake likusonyezera, iyi si hormone ya kukula (GH) koma hormone ina yomwe imatulutsa.
Ibutamoren imalepheretsanso chizindikiro cha somatostatin receptor. Kuphatikiza apo, imakulitsa chizindikiro cha GHRH mu somatotrophs ya anterior pituitary gland. Nutrobal imathandizira kuchepetsa kutulutsidwa kwa somatostatin, chinthu chomwe chimalepheretsa kutulutsidwa kwa mahomoni okula m'thupi.
Kafukufuku amasonyeza zimenezo Nutrobal, kapena Ibutamoren, ikhoza kupititsa patsogolo kukula kwa mahomoni m'thupi. Imachita izi potengera zochita za ghrelin, timadzi tambiri timene timalimbikitsa njala ndikulimbikitsa metabolism.
MK-677 imamangiriza ku GHSR, imodzi mwa ma androgen receptors mu ubongo. Ndizofunikira kudziwa kuti GHSR yotsegulidwa imathandizira kukula kwa hormone kutulutsa muubongo.
Pochita izi, Nutrobal imathandizanso zinthu zingapo, kuphatikizapo:
- Kulakalaka;
- Nyimbo zachilengedwe;
- Kukumbukira;
- Kuzindikira;
- Chikhalidwe;
- Kusangalala komanso kukhala ndi moyo wabwino.
Imodzi mwa mabhonasi a Nutrobal ndikuti imathandizira kuchuluka kwa mahomoni okula osakulitsa kuchuluka kwa mahomoni ena monga cortisol.
Zina mwazotheka zomwe zingakhalepo zingaphatikizepo: mawonekedwe abwino, kuchuluka kwa mphamvu ndi mphamvu, kupirira kowonjezereka, kaphatikizidwe ka mapuloteni, komanso kusungidwa kwa nayitrogeni.
Nayitrogeni ndi gawo lofunikira la ma amino acid omwe amapanga mapuloteni. Chifukwa chake, thupi likakhala ndi nayitrogeni wabwino, limakhala ndi zinthu zokonzanso zovulala ndikupanga milingo yofunikira ya mahomoni.
Kafukufuku wambiri anenanso kuti MK-677 imalimbikitsa kuyankha kwamphamvu m'thupi.
Chinthu chinanso chodziwika bwino cha MK-677 ndikuti sichimapikisana ndi kukula kwa timadzi tating'onoting'ono tomwe nthawi zambiri timagwirizanitsa ndi kayendetsedwe ka hormone ya kukula kwaumunthu. Zotsatira zake, mutha kugwiritsa ntchito Nutrobal kwa HGH cycle, kupereka kuwonjezeka kwachilengedwe kwa GH pulses. Zikutanthauzanso kuti simuyenera kuthana ndi jekeseni zowawa kapena zosasangalatsa za tsiku ndi tsiku za kukula kwa munthu.
Ubwino wonsewu ukuwonetsa kuti othamanga, omanga thupi, ndi ena amatha kugwiritsa ntchito Nutrobal pazolinga zosiyanasiyana. Pali zabwino zambiri, kuyambira kukula kwa minofu mpaka kung'ambika.
Ubwino wa Mk-677
Ubwino waukulu wa MK-677 ndi kuwonjezeka kwa kukula kwa hormone ndi ma IGF-1. Hormone ya kukula imathandizira kukonza minofu, kukula kwa minofu, ndi kutaya mafuta. IGF-1 ndiyofunikira pakukula kwa maselo ndi kusinthika.
Imawonjezera Kumanga Kwa Minofu
Ibutamoren imakhala yothandiza kwambiri polimbikitsa kuwonjezeka kwakukulu kwa thupi lochepa thupi. Ikuwonetsanso mphamvu yofananira yowonjezera minofu, mphamvu ya minofu, ndi kutanthauzira kwa minofu pamene kuchepetsa mafuta a thupi.
Amachepetsa Kuwonongeka Kwa Minofu
Ibutamoren ndi mankhwala abwino kwambiri ochepetsera kulemera kwa zakudya zomwe zingatheke ndi kuwonongeka kwa minofu. Kuphatikiza apo, Nutrobal imatha kupititsa patsogolo kuthamanga kwa gait ndi mphamvu ya minofu. Ikhozanso kuchepetsa chiwerengero cha kugwa kwa odwala okalamba omwe ali ndi fractures ya m'chiuno.
Imakulitsa Ubwino wa Tulo
Kafukufuku wa sayansi wasonyeza kuti Ibutamoren imatha kukhudza nthawi ya kugona kwa REM komanso kugona kwathunthu. Mofanana ndi ghrelin, imapangitsa kuti circadian rhythm iwonetseke ndipo imalimbikitsa kugona kosasinthasintha komanso kosasokonezeka. Chotsatira chake, omwe amatenga Ibutamoren nthawi zambiri angapeze kuti amatha kugona bwino komanso amatsitsimutsidwa atadzuka.
Imakulitsa Moyo Wautali
Ibutamoren ikhoza kupititsa patsogolo ma IGF-1 ndi kukula kwa hormone m'thupi, yomwe ili ndi ubwino wambiri. Kuperewera kwa IGF-1 kulipo mwa omwe ali ndi vuto la kukula kwa hormone ndipo kungayambitse mafupa osalimba, minofu yochepa, ndi kusintha kwa lipids. Ndiwoyenera kwa anthu omwe akukumana ndi kuchepa kwa minofu ndi GH secretion. Ngakhale omwe ali ndi magawo ambiri amatha kupindula ndi zina mwazopindulitsa za Ibutamoren.
Bwino Bone kachulukidwe
Mafupa athanzi ndi ofunika, mosasamala kanthu za msinkhu, kulemera, kapena luso la masewera. Mafupa ofowoka, ofooka, kapena opindika amatha kuyambitsa kuvulala kochokera ku ngozi zowoneka ngati zazing'ono, komanso kukhala zowawa ndikuchepetsa kupita patsogolo kwamasewera anu, zitha kukhala kalambulabwalo wazovuta monga osteoporosis. Hormone yokula imakhala yothandiza kwambiri pakukulitsa chiwongola dzanja ndipo pamapeto pake kuchuluka kwa mafupa.
mu kafukufuku wa azimayi achikulire omwe ali ndi kufooka kwa mafupa, Emily Krantz, MD, anati: "Zaka zambiri mankhwala atasiya, azimayi omwe amathandizidwa ndi kukula kwa mahomoni amakhalabe ndi mafupa ochepa komanso amachepetsa kusweka."
Zotsatira za Nootropic
Nutrobal amachita mu ghrelin receptor yomwe imadziwika kuti imakhala ndi nootropic zotsatira. Amakhudza bwino ntchito yaubongo muzolimbikitsa, kukumbukira, ndi luso. Mfundo yakuti Nutrobal imapangitsanso kugona bwino komanso nthawi yayitali imathandizanso; Izi ndichifukwa choti onsewa ndi ofunikira kuti chidziwitso chiziyenda bwino.
Kuthetsa Kulephera kwa Hormone
MK-677 imapangitsa IGF-1 ndi kukula kwa hormone mwa ana omwe ali ndi vuto la GH. Imagwiranso ntchito ngati Insulin-monga Growth Factor yomanga mapuloteni 3 (IGFBP-3) mwa ana awa. Zopindulitsa izi zimachitika popanda zotsatira zoyipa pa thyrotropin, prolactin, ndi glucose.
Imathandizira Machiritso a Khungu
Phindu lina la MK-677 lomwe mungakumane nalo ndikuchira mwachangu pambuyo pa opaleshoni kapena chilonda. Nutrobal imasonyeza lonjezo labwino kwambiri lochiza kuvulala kokalamba ndi kosautsa. Zimathandizanso kumangitsa khungu lotayirira kuphatikiza ma tendon ochiritsa, mafupa, ndi minyewa ndipo ndi othandizanso pakuchiritsa mabala ndi kukonzanso minofu.
Kuwonjezeka kwa collagen kumayambitsa izi, ndipo MK-677 ingakhale yoyenera kuganizira ngati mukupeza kuti nthawi yanu yochira ikuchepa pamene mukukalamba. Gulani ma SARM ogulitsa tsopano ndikumva kusiyana kwa inu nokha!
Bwino Shredding
Ogwiritsa ntchito a MK-677 ambiri ali ndi nkhawa za momwe chinthu chomwe chimakulitsa ghrelin ("hormone ya njala") chingathandizire akafuna kukhalabe ndi vuto la kalori.
Mphamvu yocheperako, ghrelin, imawonjezera njala ndikukuthandizani kudya zopatsa mphamvu zambiri. Nthawi yomweyo, imagwira ntchito yofunika kwambiri pakuwongolera kugwiritsa ntchito mphamvu (mafuta osungidwa).
Mukasankhidwa mosamala komanso mogwirizana ndi upangiri wa dokotala wanu, palibe cholakwika powonjezera mankhwala ena kuti athane ndi zotsatirazi ndikuthandizani kuchepetsa kulakalaka njala. Werengani positi yathu pa stacking kuti mudziwe zambiri za kuphatikiza mosamala zowonjezera zowonjezera pazotsatira zingapo.
Komabe, zida zomanga minofu ya Nutrobal zimakuthandizani kuti musungire zomwe mwapeza movutikira, ngakhale mutakhala ndi kalori.
Amachepetsa Kuwonongeka Kwa Nayitrogeni
Phindu lomaliza la Ibuatmoren ndiloti lingathe kuthandizira kubwezeretsa kuwonongeka kwa nayitrogeni m'thupi.
Kuwonongeka kwa nayitrojeni kumachitika pamene mpweya wa nayitrogeni wa munthu umaposa kuchuluka komwe amatenga ndikupangitsa kuti thupi likhale lolimba. Izi zidzatsogolera kutayika kwa mafuta ndi minofu pakapita nthawi ndipo sizoyenera kwa iwo omwe akuyang'ana zambiri! Ibutamoren imabwezeretsanso mlingo wa nayitrogeni mwa omwe ali ndi miyeso yochepa ndikuisunga mofanana.
Zotsatira za Mk-677
Zotsatira za Prolactin
Ibutamoren ikhoza kuwonjezera ma prolactin. Prolactin ndi timadzi tomwe timapanga mkaka ndikuwongolera chitetezo chamthupi. Pakufufuza pa makoswe, Ibutamoren inachulukitsa ma prolactin pambuyo pa masiku a 14 a mankhwala.
Zotsatira Zam'mimba
Ibutamoren ikhoza kuyambitsa zotsatira za m'mimba monga kutsekula m'mimba, nseru, ndi kusanza. Mu kafukufuku wa makoswe, Ibutamoren inayambitsa zotsatira za m'mimba pambuyo pa masiku a 14 a mankhwala. Komabe, sizikudziwika ngati Ibutamoren ili ndi mankhwala omwewo mwa anthu.
Malamulo a Hormone
Ibutamoren ikhoza kusintha ma hormone. Pakufufuza pa makoswe, Ibutamoren inachulukitsa kukula kwa hormone, IGF-1, ndi ma prolactin pambuyo pa masiku a 14 a mankhwala. Zimatsimikiziridwabe ngati Ibutamoren ili ndi zotsatira zofanana mwa anthu. Ibutamoren nthawi zambiri imaloledwa bwino, koma deta yachitetezo cha nthawi yayitali ikusowa. Palibe zotsatira zoyipa zomwe zimadziwika ndi kugwiritsa ntchito Ibutamoren.
Hypo-Pituitary Desensitation
Ibutamoren ikhoza kuyambitsa hypo-pituitary desenitisation. Apa ndi pamene pituitary gland imakhala yochepa kwambiri ndi kukula kwa mahomoni. Pofufuza pa makoswe, Ibutamoren inachititsa kuti hypo-pituitary desenitisation iwonongeke pambuyo pa masiku a 14 a mankhwala. Komabe, ikudziwikabe ngati Ibutamoren ili ndi zotsatira zofanana mwa anthu.
Nutrobal Half-Life
Theka la moyo wa Nutrobal ndi pafupifupi maola 4 mpaka 6. Choncho, akatswiri amalangiza mlingo kawiri pa tsiku wa Nutrobal. Amuna ogwiritsa ntchito amatha kutenga milingo iwiri yofanana ya 12.5mg kamodzi m'mawa komanso madzulo. Ogwiritsa ntchito azimayi amatha kutenga pakati pa 2.5 ndi 7.5mg, kamodzi m'mawa komanso kamodzi madzulo.
Nutrobal imayikidwa bwino ndi ma SARM ngati Ostarine (MK-2866), Andarine (S-4), LGD-4033ndipo Cardarine (GW-501516). Ndi bwino mu a kudula okwana kuzungulira ndi Ostarine, S-4, ndi Cardarine. Ithanso kupakidwa ndi Ligandrol kuti mumve zambiri za minofu. Pakudulira, Nutrobal imatha kupakidwa milingo iwiri ya 12.5mg tsiku lililonse. Amuna ayenera kugwiritsa ntchito 20mg Cardarine tsiku lililonse ndi iwo kwa masabata a 10-14. Yang'anani nthawi zonse ndikutsatira malangizo a m'dera lanu chifukwa malamulo owonjezerawa amasiyana.
Nthawi zonse amalimbikitsidwa kutero khalani otetezeka ndi mankhwala ozungulira posachedwa. Pachifukwa ichi, ganizirani kugwiritsa ntchito Ma Labs Omangidwa Ndi Thupi Athandizira Makapisozi 90 zothandizira mkombero. Kugwiritsa ntchito Ma Labbu Omanga Omanga Ma PCT 90 Makapisozi a Post Cycle Therapy amalimbikitsidwanso. Gulani ma ARV kuti mugulitse tsopano.
Momwe Mungagwiritsire Ntchito Ibutamoren
Nutrobal imatsimikiziridwa kuti ndiyothandiza komanso yopanda vuto. Zimapereka zotsatira zabwino kwambiri popanda zotsatira zochepa. Nthawi yabwino yoti mutenge MK-677 ndi nthawi yogona.
Simufunikanso kuchepetsa kuloledwa kumazungulira, koma ngati muli ndi nkhawa, nthawi yovomerezeka yamaphunziro ndi masabata 12 pakadutsa milungu 6 nthawi zambiri. Mankhwalawa ndi oyenera kupindula kwakukulu komanso kuwotcha mafuta.
Mk-677 Mlingo
Malinga ndi akatswiri, mulingo woyenera kwambiri ndi 20 mpaka 30 mg. Kuchulukitsa mlingo wopitilira 30 mg sikupereka zotsatira zowonjezera.
Mukatenga Ibutamoren, nthawi ya maphunziro ndi yofunika kwambiri kuposa mlingo wa tsiku ndi tsiku. Chifukwa chake, kugwiritsa ntchito MK-677 kuyenera kukhala kwanthawi yayitali. Kukula kwa mahomoni kumakwera pang'onopang'ono pakadutsa milungu ingapo.
Akatswiri olimbitsa thupi amalimbikitsa kutenga Ibutamoren pamlingo wotsatira watsiku ndi tsiku, kutengera ntchito yomwe ilipo:
- Kuchuluka minofu kukula - 30 mg.
- Kuwotcha mafuta - 20 mg.
- Kuchiritsa kuvulala ndi kuchira - kuyambira 10 mpaka 20 mg.
- Kwa oyamba kumene opanda chidziwitso ndi Ma ARV kapena mankhwala ena, kuyambira ndi mlingo osachepera 10 mg tikulimbikitsidwa, mosasamala zolinga.
Zomwe Muyenera Kusamala
Ndikofunika kuzindikira apa kuti Nutrobal sikulangizidwa kuti igwiritsidwe ntchito pakati pa amayi apakati kapena oyamwitsa, ndipo sayenera kugwiritsidwa ntchito ndi ana ndi/kapena osakwana zaka 21. Omwe ali ndi ziwengo ku zinthu zomwe zimagwira ntchito kapena zosagwira ntchito ayeneranso kupewa kugwiritsa ntchito Nutrobal. Kugwiritsiridwa ntchito kwa secretagogue ya GH kuyenera kupangidwa nthawi zonse pambuyo pa malingaliro achipatala.
Kumbukirani kuti Mlingo wa mankhwalawa owonjezera mphamvuyi sayenera kusinthidwa popanda kulangizidwa ndi achipatala. Mulimonse momwe zingakhalire, musawonjezere mlingo wanu popanda kulangizidwa ndi achipatala chifukwa izi zingayambitse kumwa mopitirira muyeso kapena kuzunzidwa.
Mk-677 vs. Hgh
MK-677 ndi secretagogue ya kukula kwa nthawi yayitali yomwe muyenera kuitenga pakamwa. Imatsanzira kukula komwe kumawoneka mu GH. Kugwiritsa ntchito MK-677 tsiku lililonse kumatha kukweza milingo ya GH ndi IGF1 kwambiri mwa achinyamata athanzi popanda kubweretsa zotsatira zoyipa.
Human Growth Hormone, yomwe imadziwikanso kuti Somatropin mu mawonekedwe ake onse, ndi hormone yomwe imalimbikitsa kukula pakati pa ziwalo zonse za thupi laumunthu. Izi zikuphatikizapo kubadwanso kwa mafupa ndi kuberekana kwa maselo. HGH ndiyofunikira kuti minyewa muubongo wathu ndi ziwalo zina zikhale zathanzi.
Mk-677 Pakati pa Pct
PCT ndi nthawi yomweyo mutangoyimitsa AAS ndipo ingaphatikizepo mankhwala osiyanasiyana kapena machitidwe kuti muchepetse kusintha kwa kusiya kugwiritsa ntchito PIED.
Mutha kugwiritsa ntchito MK-677 pa PCT kukuthandizani kubwereranso ndikukhalabe ndi mphamvu. Mudzazindikira kuti pafupifupi nthawi zonse ndi gawo la Zithunzi za PCT—ndipo pazifukwa zomveka.
Komwe Mungagule Mk-677
Monga mukuwonera, MK-677 itha kukhala yosinthira masewera athanzi komanso thanzi lanu. Kutha kwake kukulitsa misa ndi minofu ndikulimbitsa thupi ndikodabwitsa kunena pang'ono.
Masitolo a SAR ku UK akulonjeza kuti mudzatha kugula Nutrobal yapamwamba kwambiri yomwe ikupezeka pa intaneti. Mwa kunyamula MK-677 nthawi zonse kafukufuku, tikukutsimikizirani kuti mudzalandira zabwino kwambiri.
Kumbukirani, msika wa Selective Androgen Receptor Modulators nthawi zina umakhala wodalirika. Izi ndichifukwa choti ma SARM amaletsedwa ndi mabungwe monga WADA, USADA, ndi UKAD pamipikisano yambiri yamasewera.
Nthawi zonse samalani ndi kufufuza musanapange zisankho, makamaka zokhudza thanzi lanu. Funsani katswiri kuti akuvomerezeni ndi malangizo kuti mupeze zotsatira zabwino kwambiri. Nthawi zonse zimakhala bwino kupita ndi mtsogoleri wamakampani, chomwe ndi chimodzi mwa zifukwa zomwe SARMs Store ili ndi makasitomala omwe amawasirira kuchokera kudziko lonse lapansi.