RAD-140 Testolone - Master Master
Zidzakhala zosangalatsa komanso zosangalatsa bwanji kuyendetsa china chake chomwe chimatipatsa zabwino zonse za Testosterone koma osakhala ndi zotsatirapo? Lingaliro ili limamveka bwino kwa aliyense kuchokera pagulu lomanga thupi popeza tonsefe tinakhalapo ndipo tinkafuna kuti china chake chichitike m'moyo wathu. Chodabwitsa ndichakuti, zakhala pafupifupi zaka zana limodzi komanso kupitilira apo Testosterone idapangidwa koyamba koma sitikudziwapo kanthu pazinthu. Nayi nkhani yabwino!
Wosankha androgen receptor modulator wodziwika ndi dzina Mayeso (RAD-140) nditha kuzichita. Ochita masewera padziko lonse lapansi akhala akugwiritsa ntchito mankhwala ozizwitsawa kwa zaka zambiri tsopano ndipo makampani ambiri ofufuza akhala akugulitsa RAD-140 kuti athandize makasitomala awo ndi kafukufuku wa sayansi.
Kodi Testolone (RAD-140) Ndi Chiyani?
Kusankha kwa androgen receptor modulator (SARM), Testolone (RAD-140) itha kufotokozedwa ngati njira ina yabwino yothandizira m'malo mwa Testosterone. Kugwiritsa ntchito mankhwalawa kumalumikizidwa ndi maubwino osiyanasiyana, kuphatikiza koma osangolekerera kupewa kuwonongeka kwa minofu, kuwonjezeka kwa minofu yowonda, kukonza bwino ndikuchira, kukhala bwino, kutaya kwamimba ndi mafuta owoneka bwino, bwino nyonga ya thupi, ndikuchita bwino komanso kosangalatsa m'chipinda chogona.
Testolone (RAD-140) idapangidwa koyambirira kuti ipewe zovuta zoyipa za jakisoni ndi mafuta munthawi ya testosterone m'malo mwake. Nthawi zambiri, kugwiritsa ntchito mafuta kumatha kubweretsa zotupa, kuzipukuta, ndikufalikira kwa ena. Kuphatikiza apo, jakisoni wocheperako kapena wolowa mumtsempha wambiri umadziwika kuti umayambitsa abscess, matenda, mavuto amisempha, kugawana singano, ngakhale matenda opatsirana pogonana chifukwa chogawana singano. Ndi Testolone, izi sizodandaula chifukwa zimatha kudyedwa pakamwa.
Kuphatikiza pa maubwino awa, kugwiritsa ntchito Testolone sikukugwirizana ndi kukulitsa kwa Prostate ndipo sikumabweretsa tsitsi kapena kuwonongeka pamutu. Ngati sizokhazi, kugwiritsa ntchito Testolone ngati mogwirizana ndi malingaliro azachipatala sikumabweretsa zotsatira zoyipa za estrogenic monga kuphulika, gynecomastia, kusungika kwamadzimadzi, kapena kuchuluka kwamphamvu zamagazi.
Testolone motsutsana ndi Testosterone-Action Mechanism ya Testolone
Zidzakhala zovuta kwa owerenga koyamba za Testolone kuti amvetsetse momwe zinthu zimamveka bwino kwambiri komabe chinthu chotchedwa RAD-140 sichimabweretsa mavuto.
Testolone, posankha androgen receptor modulator, imasankha mwachilengedwe. Mgwirizanowu uli ndi 90 mpaka 1 anabolic to androgenic ratio. Ichi ndi gawo labwino kwambiri la RAD-140 popeza zotsatira zoyipa zambiri zomwe zimakhudzana ndi anabolic androgenic steroids zimachokera ku zotsatira zake za androgenic. Ndikofunikanso kudziwa apa kuti mufunika 40 peresenti ya Testosterone pamlingo wofanana wokula kwa minofu monga Testolone. Chofunika kwambiri ndikuti muyenera kutenga Testolone kangapo 60 kuti muyambe kuyambitsa zovuta zilizonse zokhudzana ndi Prostate.
Kuphatikiza apo, Testolone siyimveketsa mafuta a estrogen komanso siyimasinthidwa kukhala dihydrotestosterone (DHT) yomwe imatanthawuza zovuta monga kutayika kwa tsitsi ndi prostate wokulitsidwa motero satha.
RAD-140 imatha kulumikizana ndi ma receptors a androgen m'mafupa ndi minofu. Komabe, sizimayambitsa zolandilira a androgen m'malo ena amthupi la munthu. Izi zikutanthauza kuti mutha kukhala otsimikiza zakutulutsa kwa anabolic koma osapondereza mahomoni ndi zovuta zina. Chigawochi chimakhalanso ndi mphamvu yapadera yolimbikitsira kukulira kwa minofu pamlingo wocheperako kuposa zomwe zikadatha kukulitsa kukulitsa kwa Prostate. RAD-140 ndi anabolic wathunthu paminyewa ndipo imawonetsa mphamvu zochepa pamatumba am'mimba ndi prostate. M'malo mwake, Testolone imatsutsana ndi kukondoweza kwa ma seminal vesicles (pang'ono) oyambitsidwa ndi Testosterone.
Tiyeni timvetsetse zonsezi m'njira yosavuta. Mukayamba kugwiritsa ntchito mahomoni achilengedwe monga Testosterone, LH yanu (luteinizing hormone) ndi FSH (follicle stimulating hormone) imatsikira mpaka zero. Izi ndichifukwa choti tiziwalo tating'onoting'ono tomwe timatulutsa matupi amthupi zimalandira chisonyezo choti sizingathenso kugona. Mwanjira ina, thupi lanu limasiya kutulutsa mahomoni. Kumbali inayi, Testolone imapondereza zocheperako chifukwa chake nthawi zonse mudzakhala bwino kuti muchiritse msanga.
Zida za Neuroprotective Za Testolone
Kafukufuku wamankhwala atsimikizira kuti Dihydrotestosterone komanso testosterone ali ndi kuthekera kwachilengedwe kosunga ma neuron. Izi zimathandizira pakulimbikitsa zotsatira zabwino paumoyo wamitsempha wamunthu. Chifukwa chake sizosadabwitsa kuti zovuta zambiri monga matenda a Alzheimer's zimachitika ndi anthu omwe ali ndi zofooka za androgenic.
Komabe, kugwiritsa ntchito Testosterone kwa nthawi yayitali kumatha kubweretsa zovuta komanso zovuta zathanzi. Pakadali pano, RAD-140 imakhala yofanana ndi Testosterone muubongo wamunthu ndipo izi zimapangitsa kuti ikhale yopindulitsa kwambiri popewa matenda opatsirana pogonana. Kuphatikiza pa maubwino onse awa ndi zotsatira za ma SAR, Testolone imatha kuchepetsa kwambiri kufa kwa cell pambuyo poti stroko yachitika.
Udindo Wa Androgens Ndi Kusowa kwa Androgen
Androgens ndi mahomoni a steroid (monga dihydrotestosterone, androstenedione, ndi testosterone) omwe amapezeka mwa amuna ndi akazi. Mahomoniwa amatha kutulutsa minofu, chiwindi, mafupa, ndi ubongo kupatula apo adagwira gawo lofunikira pakukula ndikugonana. Palibe amene angakane kuti amuna komanso akazi amafuna kuchuluka kwa ma androgen kuti akhalebe athanzi. Komabe, mahomoniwa amayamba kuchepa tikamakalamba.
Ichi ndichifukwa chake okalamba amakumana ndi mavuto osiyanasiyana azaumoyo monga kulumala, kutayika kwa minofu, kuchepa mphamvu, ndi mafupa osweka. Kutsika kwa mayendedwe a androgens kumalumikizidwanso ndikukula kwa zovuta zazikulu monga Acquired Immuno-deficiency syndrome, kulephera kukula, ndi khansa.
Ogwira ntchito zamankhwala padziko lonse lapansi amalimbikitsa mankhwala othandizira a Testosterone kuti athetse matenda omwe amakhudzana ndi kuchepa kwa androgen. Komabe, kugwiritsa ntchito testosterone yopanga nthawi zonse kumalumikizidwa ndi chiwopsezo china ndi zovuta zina, zina zomwe zimakhala zovuta monga kusabereka kwa azimayi ndi khansa ya prostate mwa amuna. Izi ndi zina mwazifukwa zomwe Testolone ikucheperachepera pang'onopang'ono ndikukhala chisankho kwa anthu omwe akufuna njira ina yabwino.
Ubwino Wina Wa RAD-140
Tinawerenga kale zambiri za zabwino zosawerengeka za RAD-140. Komabe, pali zabwino zambiri za Testolone zomwe titha kuwerenga.
Kuchulukitsa Mass Mass
Matenda ambiri monga Edzi, multiple sclerosis, ndi khansa zimayambitsa zovuta zina monga cachexia kapena kuchepa kwa thupi pokhudzana ndi mafuta ndi minofu. Izi zimabweretsa kuwonongeka kwa minofu kapena kutayika kapena minofu ya minofu, kufooka, ndi kutopa zomwe zimapangitsa kuti ntchito yonse yochiritsa ndikuchira ikhale yovuta kwambiri. Zomwe sizingafanane ndi zomangamanga za RAD-140 zimapangitsa kuti akhale woyenera kuthana ndi mavuto awa ndi ena ambiri powonjezera kunenepa. Zimachitika pothandiza kukula kwa mafupa ndi minofu. Ichi ndichifukwa chake akatswiri azachipatala amapereka RAD-140 kwa odwala omwe ali ndi khansa ya prostate.
Monga ma SAR, ma RAD-140 amatsanzira phindu la Testosterone ya ma powerlifters ndi omanga thupi. Izi zimachitika pochepetsa kuchepa kwa minofu yamafuta, kukulitsa minofu, ndikulimbitsa kupirira komanso kulimba mtima panthawi yophunzitsira kwambiri komanso kulimbitsa thupi.
Amachiza Khansa ya m'mawere
Testolone yawonetsa lonjezo lalikulu pochiza khansa ya m'mawere kwa odwala omwe ali ndi androgen ndi estrogen receptors (khansa ya m'mawere ya AR / ER +). Kugwiritsa ntchito RAD-140 ngati gawo la chithandizo mwa odwalawa kwawonetsa kuti kupondereza kwakukulu kukula kwa maselo a khansa poletsa zotsatira za estrogen paminyewa. Makamaka, Testolone imaletsa kupanga ESR1, yomwe ndi protein yomwe imathandizira pakukula kwa khansa.
Amachiza Matenda a Neurodegenerative
Testolone imatha kuteteza mitsempha yaubongo kuti isavulazidwe ndi mapuloteni amyloid beta omwe amachititsa kuti matenda a Alzheimer's akule. Ndikofunikira kudziwa apa kuti ma androgens nthawi zambiri amatha kuchepetsa kuchuluka kwa mapuloteni amyloid beta. Kuphatikiza apo, zimathandizira kukula kwa kukula kwa maselo amubongo ndi synaptic plasticity zomwe ndizofunikira pamakumbukidwe ndi kuphunzira.
Mlingo Ndi Chithandizo Cha Kutumiza Kwambiri
Testolone imaperekedwa pamankhwala a tsiku ndi tsiku a 20 mpaka 30mg, makamaka omwe amatengedwa pakamwa, masabata a 8-12. Chithandizo cham'mizeremizere chikulimbikitsidwa mutagwiritsa ntchito RAD140 kuti mahomoni abwerere m'thupi lawo. Itha kudzazidwa ndi Ostarine (MK-2866) ndi Ibutamoren (MK-677).
Kumene Mungagule Testolone?
Masitolo a SARM, SARMs yaku UK yaku bizinesi yayikulu pamilandu yalamulo komanso kafukufuku wama SARM, ndiye chisankho chofunikira kwambiri padziko lonse kugula kalasi ya kafukufuku Testolone (RAD-140). Chofunika kwambiri pamagulitsidwe apa intaneti ndikuti chidziwitso chanu chovuta chimasungidwa nthawi zonse ndipo simupeza chilichonse, koma osati Testolone yabwino pamtengo wodabwitsa. Lingaliro ili likuthandizani kupeza ma SARM abwino kwambiri omwe amapereka zotsatira zabwino za SARM. Sikuti chifukwa Sitolo ya SARM ili ndi ndemanga zabwino kwambiri za SARM pa intaneti chifukwa cha zopangidwa zake zoyambirira, komanso chifukwa zimatsindika kwambiri pazogulitsa zamakasitomala apamwamba.