Kodi ma SAR ndiotetezeka?

Ma SAR (Selective Androgen Receptor Modulators) atchuka kwambiri ku UK, US, ndi madera ena adziko lapansi chifukwa chakumanga minofu ndi kuwonda. Sakhala ngati mankhwala achikhalidwe, chifukwa samatulutsa zotsatira zoyipa zomwezi, ndipo othamanga ambiri, ophunzitsa, komanso ophunzitsa kulimbitsa thupi amawagwiritsa ntchito kuti akhalebe ndi thupi lolimba.

Njira yokhayo mudzawona zabwino zakugwiritsa ntchito ma SAR ndikusankha mtundu wodziwika bwino ndikumwa mankhwala oyenera. Pali mitundu yosiyanasiyana ya ma SAR, ndipo iliyonse imakhala ndi kutalika kosiyanasiyana. Mukamagula ma SAR, werengani chizindikirocho mosamala ndikutenga ndalama zofunika munthawi yoyenera. Ma SAR ena monga Ibutamoren amatengedwa bwino usiku, pomwe ena amatengedwa kamodzi kapena kawiri patsiku kutengera momwe amagwirira ntchito.

 

Ubwino wama SAR: Kodi ma SAR ndi Otetezeka?

• Ma SAR akhoza kukupindulitsani m'njira zambiri. Amathandizira kuchiritsa kuvulala kwakale, amachepetsa kuchuluka kwa mafupa, komanso amathandiza anthu omwe ali ndi vuto la prostate. Mosiyana ndi mankhwala ena samawononga chiwindi pochita izi. 
• Ofufuza akugwiranso ntchito ma SAR ngati mankhwala a matenda a Alzheimer's and osteoporosis mtsogolo. 
• Ma SAR ndi omwe alibe poizoni, ndipo amapereka maubwino a zowonjezera za anabolic pomwe amachepetsa zovuta za testosterone.

 

Ma SAR ali ndi mphamvu yamphamvu kwambiri ya anabolic, ndipo amalumikizana ndi ma receptors mosankha kuti athandize kulimbitsa thupi komanso kulimbitsa thupi. Zotsatira zake mu ma SAR zimachepetsedwa kwambiri poyerekeza ndi anabolic steroids chifukwa chaichi, chifukwa amangogwira pama receptors omwe amachita zomwe anabolic amachita. Zinthu zamankhwala izi zimathandizira kuwotcha mafuta mwachangu, ndichifukwa chake amagwiritsidwa ntchito ngati zowonjezera anthu omwe akufuna kukhala olimba. Zowonjezera za SARM zitha kulowetsedwa mosavuta pakamwa popanda kufunikira jakisoni iliyonse.

Pali mitundu yambiri yama SAR yomwe ilipo yomwe imagwiritsidwa ntchito mosiyanasiyana. Ma ARV wamba omwe amadziwika ndi kupindula kwa minofu ndikuwonjezera kuchepa kwa minofu ndi RAD-140, LGD-4033 ndi Andarine (yemwenso amadziwika kuti S4).

Mtundu wofala kwambiri wa SARM womwe umagwiritsidwa ntchito pakupanga mphamvu ndi MK2866, kapena Ostarine. RAD-140 ndi anabolic kwambiri kuti itha kugwiritsidwanso ntchito kupititsa patsogolo mphamvu. Komabe, ndi yamphamvu kwambiri kuposa Ostarine, chifukwa chake imayenera kumwedwa pang'ono.

Pomanga minofu yambiri, ma SAR ngati SR-9009, GW-1516, ndi MK-677 (Ibutamoren) amagwiritsidwa ntchito kwambiri. MK-677 imathandizanso kukulitsa kugona, ndipo anthu omwe amavutika kuti agone, kugona tulo, kapena kupeza tulo tabwino kwambiri atha kupindula ndi izi. 

Ma ARV amachepetsa kuwonongeka kwa mapuloteni omwe amathandiza pakupanga minofu ya minofu. Ntchito zawo za anabolic zothandizira kukulitsa thupi lowonda, zomwe zikutanthauza kuti kulemera kwanu komwe kumakhalako kudzakhala kopanda mafuta komanso kopanda madzi. Izi zimatsimikizira kuti thupi limapangidwa bwino osangowonjezera kulemera kwa madzi komwe kudzatayikenso nthawi yomweyo.

Ma SAR angathandizenso kulimbikitsa minofu, kotero omanga thupi amatha kunyamula zolemetsa zolemetsa mosavuta komanso zochulukirapo pakapita nthawi. Kumeza pakamwa pazowonjezera kumatanthauza kuti ndiotetezeka kugwiritsa ntchito poyerekeza ndi jakisoni yemwe angayambitse matenda apakhungu, kapena vuto la kuipitsidwa ngati sapatsidwa moyenera.

 

Zotsatira Zoopsa

Mutha kuwona zotsatira zoyipa kapena zovuta ngati simutenga zowonjezerazo pamlingo woyenera, kapena ngati simumaliza kumaliza ma SARM onse. Kuphatikiza apo, muyeneranso kukhala ndi zakudya zopatsa thanzi komanso kuchita masewera olimbitsa thupi pafupipafupi, kuti muwone zabwinozo munthawi yochepa.

Ichi ndichinthu chatsopano m'thupi lanu ndipo kuchuluka kwa izi kumatha kukupanikizani, kukupangitsani kukhala ndi zovuta zoyipa ndikuchepetsa kupita patsogolo kwanu. Mkati ndi kunja kwaulendo wanu wolimbitsa thupi, thanzi liyenera kukhala patsogolo komanso chakudya chopatsa thanzi, kugona mokwanira, komanso kafukufuku woyenera ndiye maziko abwino amtundu uliwonse wamasewera. Mukamayesetsa kuchita zinthu zomangirira, mudzapeza zotsatira zabwino.

Monga tanenera kale, ndikofunikira kuti mugulitse pafupi ndikuwonetsetsa kuti mukungogula zowonjezera kuchokera kuzinthu zodziwika bwino. Pano pa Masitolo a SARM, timagulitsa ma SARM abwino kwambiri: oyesedwa, oyesedwa, ndi opangidwa ku UK ndi ma Bodybuilt Labs. 

 

Kodi ma SAR ndi Otetezeka ndi a FDA Amavomerezedwa?

Pali zokambirana zazikulu komanso zopitilira funso loti, "ma SAR ali otetezeka?". Tsoka ilo, sitinapezebe chilichonse chomveka chokhudza chitetezo cha mankhwalawa kwa nthawi yayitali. Kuphatikiza apo, Food and Drug Administration (FDA) kuyambira 2021 sanawone ma SAR ngati chinthu chovomerezeka kuti atenge. Nthawi zambiri, ma SAR amapezeka kuti mugule koma kungopeza kafukufuku. Ngakhale ndizololedwa kugwiritsa ntchito ma SAR pazinthu zina, muyenera kukumbukira izi nthawi zonse ndikufunsani magulu angapo aboma kuti akuwongolereni. 

 

Kodi ma SAR ndi ovomerezeka?

Ma SAR ndi mankhwala omwe amapezeka pafupifupi padziko lonse lapansi. Ku US ndi UK, ndizovomerezeka kugula kapena kugulitsa ambiri. Ngati wina akufuna, atha kuchita.

Komabe, m'maiko ena monga Australia, ma SAR samatsegulidwa kwa onse: pali zoletsa. Mutha kuwapeza moyenera pokhapokha mutalandira mankhwala akuchipatala. 

 

Kodi Dokotala Angandipatse Ine Ma SARM?

Ma ARV akadali mankhwala omwe amafufuzidwa ndi a FDA. Chifukwa chake, sikungakhale koyenera mwalamulo kuti dokotala wanu akuuzeni kuti muwamwe. Madokotala ovomerezeka sangathe kupereka ma ARV mwachindunji. Komabe, monga momwe akugwiritsidwira ntchito ndi FDA, ngati wothamanga aliyense akufuna kuyesa mankhwalawo mwaufulu, atha kutero - koma adzafunika kukhala ndi Therapeutic Use Exemption (TUE) yochokera ku USADA.

Izi zimaperekedwa mokhazikika komanso mosabisa, ndipo zimapatsa mwayi ogwiritsa ntchito mwayi wogwirizana ndi World Anti-Doping Agency International Standards. Izi zitha kukhala zazitali ndipo zimangoperekedwa ngati muli ndi zachipatala kapena zochitika zomwe zimafunikira kugwiritsa ntchito ma SAR. Izi zati, sizosatheka, kapena mndandandawo sungakhaleko. 

Za izi, USADA akuti:

"Ntchito yofunsira TUE ndiyabwino ndipo yapangidwa kuti ikwaniritse kufunika kopatsa othamanga mwayi wopeza mankhwala oyenera ndikuteteza ufulu wa othamanga oyenera kupikisana pamunda wofanana."

Chifukwa chake, mutha kuwona kuti njirazi zakhazikitsidwa kuti zisawononge masewera oyipa kapena zoopsa zathanzi pakati pa othamanga, komanso zilipo kuti zithandizire iwo omwe amafunikira. Pazovomerezeka izi ma SARM atha kugwiritsidwa ntchito movomerezeka ngati chithandizo. 

 

Kodi ma SAR amagwira ntchito bwanji?

Ma SAR amagwira ntchito pathupi potengera androgen imodzi ya chigoba. Amapeza zotengera za androgen kuchokera mbali zosiyanasiyana za thupi ndipo zimagwira ntchito mosankha, m'njira monga kukulitsa minofu ya minofu ndikulimbitsa mafupa. Amalumikiza maselo am'mafupa ndi minofu yaminyewa: chifukwa chake, amathandizira pakupanga mapuloteni, ndikuwonjezera kusungidwa kwa nayitrogeni. 

 

Kodi ma SARM ndi Zotani?

Zosakaniza zimasiyanasiyana kutengera mtundu, koma ma SARM omwe amagulitsidwa kwambiri ndi omwe ali ndi Cardarine, Ostarine, Ligandrol, Testolone RAD-140, ndi YK-11. Kupatula izi, mavitamini ndi mchere amawonjezeredwa pazowonjezera malinga ndi zomwe mukufuna. 

 

Kodi ma SAR ndi abwino kuposa ma steroid? Kodi ma SAR ndiotetezeka?

Mukamaganizira yankho la funso loti, "ma SAR ndi otetezeka kapena ayi?", Muyeneranso kuganizira za chitetezo cha steroids. Zowona zake ndikuti ma SAR ndiabwino kuposa ma steroids kuchokera kumaonero a anthu ambiri popeza zovuta zawo zamankhwala ndi zakuthupi sizimawonekera kwakanthawi kochepa. Komabe, sizinavomerezedwe mwalamulo. 

 

Chifukwa Chiyani Ndiyenera Kugwiritsa Ntchito Ma SARM?

Ma SAR ndi amodzi mwamankhwala otchuka kwambiri okula minofu. Ochita masewera ndi omanga thupi makamaka amatha kumwa mankhwalawa kuti apititse patsogolo magwiridwe awo. Ngati mukung'ung'udza kapena mumangokonda kuwonetsa minofu yayikulu, ma SAR atulutsa zotsatira zomwe mukufuna. Komabe, muyenera kukumbukira kufunsa funso, "kodi ma SAR ndi otetezeka?" ndipo yesani ngati ndi chisankho chanzeru, chololedwa, komanso chabwinobwino kwa inu. 

Pali zifukwa zambiri zovomerezeka zomwe mungagwiritsire ntchito ma SAR ndi akatswiri azachipatala atha kukhala ofunitsitsa kukambirana nanu zosankha ngakhale sangakwanitse kuwalamula. Pansi pa Therapeutic Use Exemption yomwe tidakambirana kale, zina mwazomwe zimachitika ndikutaya kwa minofu, kufooka kwa mafupa, matenda a Alzheimer's, komanso kukula kwamahomoni. 

 

Kodi pali ma SAR mu zowonjezera zakudya?

Ngati mukuganiza kale kuti, "ma SAR ndi otetezeka?", Mudzafunika kusamala kuti muwonetsetse kuti simukugula zinthu zilizonse kuphatikiza ma SAR osadziwa. Ma SAR samalandiridwa mwalamulo kuti agwiritsidwe ntchito pazakudya zowonjezera. Ngakhale, zomvetsa chisoni, pali zowonjezera zowonjezera zakudya m'misika yomwe ili ndi ma SAR.

Izi nthawi zonse zimakhala zosaloledwa ndipo zimawonedwa ngati zakhudzana. Monga ma SAR, uwu ndi msika wovuta komanso womwe ungakhale wowopsa kuyenda ndipo muyenera kugula zakudya zowonjezera kuchokera kuzinthu zovomerezeka. 

 

Kodi ma SAR amaletsedwa pamndandanda wa World Anti-Doping Agency (WADA)?

Mndandanda wa WADA (kapena World Anti-Doping Agency) uli ndi mayina amankhwala onse oletsedwa amtundu uliwonse wamasewera. Bungweli limasintha mindandanda yake chaka chilichonse ndipo limayamba kuyambira pa 1 Januware chaka chimenecho. Malinga ndi zomwe WADA yaposachedwa kwambiri, zopangidwa ndi SARM siziloledwa kuti zizigwiritsidwa ntchito pamasewera motsogozedwa nawo. Ochita masewera sangakhale ndi mankhwalawa kuti apititse patsogolo mphamvu zawo pokhapokha atayika pamndandanda wawo monga momwe tafotokozera kale. 

 

Kodi Pali Zolemba Zilizonse Zokhudza Kugwiritsa Ntchito Ma SARM?

Anthu ambiri atenga ma SAR pamayesero azachipatala, atapatsidwa TUE kuchokera ku USADA. Nthawi zambiri, ogwiritsa ntchitowa adanenanso kuti zomwe adakumana nazo ndizopindulitsa. Ambiri adati anali okonzeka kupitiliza kugwiritsa ntchito ma SAR nthawi yayitali akangovomerezedwa pamlingo wokulirapo. Zachidziwikire, maphunzirowa akadali aposachedwa kwambiri ndipo zomwe otenga nawo mbaliwa sanadziwebe kwakanthawi: pakanthawi kochepa, zikuwoneka kuti zatulutsa zabwino. 

 

Kodi ma SARMS ndi Otetezeka kwa Akazi?

Tsopano funso ndi ili: "kodi ma SAR ali otetezeka kwa amayi?". Mutha kukhala okondwa kudziwa kuti ndizotetezedwa kuti wamkulu aliyense atenge ma ARV ena pamikhalidwe yovomerezeka, momwemonso azimayi atha. Azimayi ali ndi mwayi wambiri wodwala kufooka kwa mafupa kuposa amuna ndipo chifukwa chake, pofufuza zamankhwala, zowonjezera izi zitha kukhala zothandiza kwambiri polimbana ndi mafupa olimba komanso owopsa. Thupi lachilengedwe la azimayi limathandizanso kuti kuchepa kwamafuta kukhale kovuta m'malo ena monga m'chiuno ndi m'mimba. 

Komabe, mitundu yosiyanasiyana ya ma SARM imatha kubweretsa kusintha kosiyanasiyana, ndipo ma SAR ena amaganiziridwa kuti ali ndi zovuta zosiyanasiyana pa njira yoberekera wamkazi kuposa yamwamuna. Amayi ena angafunenso kupewa zowonjezera mavitamini zomwe zimatsanzira zotsatira za testosterone, mwachitsanzo tsitsi lowonjezeka la thupi kapena mawu otsika. Ngakhale zitakhala zotani, azimayi amafunika kumwa mankhwala ochepa kuposa amuna. 

Ma SAR amatenga minofu ndi mafupa, motero amakhala ndi zotulukapo zabwino pa aliyense amene akufuna kuwonjezera mafuta owonda kapena kuwotcha mafuta. Izi sizitanthauza kuti zotsatira zake siziyenera kuganiziridwa. Monga momwe muyenera kudzifunsa nthawi zonse ndi funso "kodi ma SAR ndi otetezeka?", Ndikofunikira kutsatira malangizo azamalamulo ndikukumbukira kuti ma SAR sakuvomerezedwa pakadali pano. Amayi omwe ali ndi pakati, atha kukhala ndi pakati, kapena akuyamwitsa sayenera kutenga ma ARV mulimonse momwe zingakhalire. 

 

Kodi ma SAR ndi ati?

Ma SAR atha kugwira ntchito yambiri mthupi lanu, ndipo zachidziwikire zimadalira moyo wanu komanso mtundu wanji wazotsatira zomwe mukufuna kukwaniritsa. Ngati mungafunse za ma SAR abwino, tikupangira Ostarine (MK-2866) mukavomerezedwa ndi zamankhwala kuti ndiwothandiza kwambiri komanso oyenera mozungulira. Kwa iwo omwe akufuna kuchepa thupi, Ligandrol (LGD-4033) imatulutsa zotsatira zomveka.

Awa ndi malingaliro omwe amapezeka povomerezedwa ndi azimayi azachipatala, chifukwa amapewa zizindikilo zambiri zomwe zimakhudzana ndi testosterone zomwe amayi ena samaziwona, kapena zimapewa kukulitsa kusintha kwa mahomoni komwe kumachitika m'moyo wa mkazi. 

Kuphatikiza apo, Myostine YK-11 imalimbitsa mphamvu ndipo Andarine S4 imapangidwira kutaya mafuta.

 

Kuti mumve zambiri, omasuka kutero Lumikizanani nafe! Titha kukhala okondwa kwambiri kukambirana zambiri za inu ngati ma SAR ali otetezeka kwa inu, yankhani mafunso anu, ndikupanga ndandanda yomwe imagwira ntchito pazolinga zanu.